COSMECEUTICAL OF HERBAL AND NATURAL ORIGIN

COSMECEUTICA
L OF HERBAL
AND NATURAL
ORIGIN
Presented by: POOJA
Roll no.: 1821
Pharmacy 1st year
(Pharmacognosy)

Cosmeceutical of Herbal and natural origin
Cosmeceutical: Cosmeceuticals is the combination of cosmetics and pharmaceuticals.
Cosmeceuticals are cosmetic products with bioactive ingredients purported to have
medical or drug-like benefits.
 The "cosmeceutical" label applies only to products applied topically, such as creams,
lotions and ointments
 According to the United States Food and Drug Administration (FDA), the Food, Drug,
and Cosmetic Act "does not recognize any such category as "cosmeceuticals". A
product can be a drug, a cosmetic, or a combination of both, but the term
"cosmeceutical" has no meaning under the law"

Herbal Cosmeceuticals
 Cosmetics containing an active ingredient obtained from plant origin
 By using different cosmetic ingredients to form the base in which one or more herbal
ingredients are used to cure various skin ailments
 Herbal cosmetics are the products in which herbs are used in crude or extract form
 The demand of herbal medicines is increasing rapidly due to their skin friendliness
and lack of side effects
 The best thing of the herbal cosmetics is that it is purely made by the herbs and shrubs
and thus is side-effects free
 The natural content in the herbs does not have any side effects on the human body;
instead provide the body with nutrients and other useful minerals

 Herbal cosmetics are the modern trend in the field of beauty and fashion
 These agents are gaining popularity as nowadays most women prefer natural
products over chemicals for their personal care to enhance their beauty as
these products supply the body with nutrients and enhance health and provide
satisfaction as these are free from synthetic chemicals and have relatively less
side-effects compared to the synthetic cosmetics

Advantages of Herbal Cosmetics over Synthetic
1. Natural products: herbal cosmetics are natural and free from all the harmful synthetic
chemicals which otherwise may prove to be toxic to the skin
Different plant parts and plant extracts are used in these products,
e.g. aloe-vera gel and coconut oil. They also consist of natural nutrients like Vitamin E that
keeps skin healthy, glowing and beautiful
2. Safe to use: Compared to other beauty products, natural cosmetics are safe to use.
Herbal cosmetics contain natural antioxidants like vitamin C

3. Compatible with all skin types: Natural cosmetics are suitable for all
skin types. No matter if you are dark or fair, you will find natural cosmetics like
foundation, eye shadow, and lipstick
Fits your budget: Natural cosmetics are not that expensive. In fact, some of these
products are more affordable than synthetic ones
No side effects: The synthetic beauty products can irritate your skin, and cause pimples
 They might block your pores and make your skin dry or oily. With natural cosmetics,
one need not worry about these
 The natural ingredients used assure no side effects; one can apply them anytime,
anywhere

Hair growth formulation
What is the hair cycle?
There are natural ways to speed up hair growth, such as leading a healthy lifestyle and
trying to keep stress levels to a minimum
An adequate amount of sleep and exercise will help to control your stress levels
Physical activity encourages your body circulation including your scalp, promoting hair
growth
Make sure to avoid fad diets, if you aren’t eating enough protein and iron you will lack
energy which will lead to hair loss as well as other deficiencies

Stages of the Hair Growth Cycle
The growth cycle of a hair consists of 3 stages:
1. ANAGEN (GROWING) STAGE
 The anagen stage is the growing period of a hair follicle
 This stage typically lasts about 3 to 5 years
2. CATAGEN (INTERMEDIATE) STAGE
 The catagen stage is the intermediate period of hair growth
 Hair follicles prepare themselves for the resting phase
 It lasts around 1-2 weeks
 During this phase, the deeper portions of the hair follicles start to collapse
3. TELOGEN (RESTING OR SHEDDING) STAGE
 The telogen stage is the resting and shedding period of the hair cycle
 It usually lasts 3 to 4 months
 At the end of this period, older hairs that have finished their life will fall out and newer
hairs will begin to grow

What is hair growth formulation?
 Herbal hair growth formulation is a wonderful blend of herbs that is effective in
treating hair loss
 This formulation is full of natural hair growth herbs which makes it effective of all
hair loss treatment

Benefits of Hair Growth Formulation
 Prevent hair loss
 Improves circulation to the head/scalp
 Helps to regenerate new hair
 Improving hair texture
 Improving hair strength
 Its helps to bring in new hair roots
 It is an anti-aging product and prevents hair aging
 Naturally increases growth of hairs
 It should have reasonable stability or shelf life
 It should easy to apply
 It should non-toxic
 It should non-irritant
 It should be economic

Formulation of hair growth by using tobacco leaves
Plant material and extraction
 Fresh leaves of tobacco were collected
 The leaves were dried under shade and macerated with cow urine for 28 days with
occasional stirring
 After filtration with muslin cloth, solvent was removed by distillation under vacuum
 The crude residue mass of extract were concentrated, stored and preserved (2-8° C)
 It is considered as a microbial biotransformed extract
INGREDIENTS QUANTITY REQUIRED( %w/w)
Herbal extract( tobacco leaves) 2
Lanoline 5
Cetyl alcohol 3
Bees wax 2
Propylene glycol 1.5
Sesame oil 1.5
Stearic acid 2

Uses of ingredients
1. Stearic acid: emulsifier, emollient, and lubricant and Also oil soluble
2.Cetyl alcohol: thickening agent, soothing the skin
3. Bees wax: thicken the consistency of formulation and soothing and lock the,
moisture
4. Sesame oil: boost hair growth and helps to get glossy and shiny hair back
5. Propylene glycol: help in penetration of active ingredients and soluble in
water
6. Lanoline: used as moisturizer and soften
7. Tobacco leaves: safe and promotes the hair growth

Preparation of formulations
Herbal lotions were prepared by general method using o/w type base. The formula of
base contains lanoline (5% w/w), Cetyl alcohol (3% w/w), bees wax (2% w/w),
propylene glycol (1.5% w/w), sesame oil (1.5% w/w), stearic acid (2% w/w),
preservative (q.s.), perfume (q.s.) is considered
 The emulsifier and other oil soluble components were dissolved in the oil phase
(Part A) and heated to 75° C
 The preservatives and other water soluble components (Methyl paraban, Propyl
paraban, Propylene glycol, all extracts) were dissolved in the aqueous phase (Part B)
and heated to 75° C
 After heating, the aqueous phase was added in portions to the oil phase with
continuous stirring until cooling of emulsifier took place

Examples of Herbal Hair Growth Formulation
ALOPECIA HAIR LOSS TREATMENT :
Main ingredient: like Rosemary, Jojoba Oil, Sea Buckthorn Oil, Flaxseed Oil,
Pumpkin Seed Extract, Essential Oils of Pink Grapefruit
Follic Grow Herbal Hair Oil:
Main ingredients: Bhringaraja, Amla, Neem, Brahmi and Tulsi
Patanjali Kesh Kanti Hair Oil:
Main ingredients: Brahmi, Amla, Bhringraj, Mehandi, Neem leaf, Harad, Aloe Vera, Haldi,
Anantmool, coconut oil, Til oil

EVALUATION METHOD OF HAIR FORMULATION
PREPARED
Evaluation of hair growth formulation was done on animal
Animals
Male albino wister rats (120-150 g) were used. The animals were fed with standard pellet
diet and water ad libitum and maintained under standard environmental conditions (22°C ±
5 °C with 12 h of light-dark cycle)
Skin irritation test:
 Preliminary skin irritation test on albino rats, the skin from the back of six rats was
shaved on both sides of the back using hair clipper and an electric shaver to exposed test
areas
 On cleaned test sites, the prepared formulations were applied and visual observations
were made for the appearance of any irritation or erythema for a total period of 72 hr.
after the application of test preparations

Quantitative hair growth study
 The method was followed for the quantitative evaluation of treatment
 Two rats from each group were euthanized after 10 days, 20 days, and 30 days of
treatment: Skin biopsies were taken from shaved area, and the specimen was preserved
in 10% formalin
 Tissues were embedded in paraffin wax and sectioned into the uniform thickness of 10
μm and stained with hematoxylin and eosin
 Sections from all the groups were evaluate for the number of hair follicles per mm area
of skin and percentage ratio of hair follicles in different cyclic phases, such as anagen
(growth phase), catagen, and telogen (resting phase), was determined microscopically

Hair length
Hair was plucked randomly from the depilated area with the help of electric clipper and
measured the hair length with the help vernier caliper Or Scale and calculated the mean
of hair length
Hair density
 A hole of 1 cm2 was made on card board
 Then the card board set on the desired depilated area (where hair fall patches
observed) on the back of rat after back of rat after 45 days of depilation
 The hair was trimmed of desired depilated area, and the hair was cut with the seizure
The hair was count manually

Fairness formulation
Define: Fairness cream gives fairness with an even tone, while cleansing dark spots,
discolored and pigmented skin
The Fairness cream is supposed not only to import fairness, but also remove blemishes
from the skin
Its natural action involves reduction of the black melanin in the skin without changing
the skin’s natural balance

Ideal characteristics of herbal fairness formulation
 Fairness cream gives sun protection
 Fairness cream protects from pollution damage
 Fairness creams makes your skin glow
 Fairness cream lightens age spots and pigmentation patches
 They maintain the pH. level of your skin.so your skin does not feel excessive oily or
acutely dry
 Effectively lightens overall complexion
 Skin glowing effect
 Nourishes the skin

Material and Methods
2.1 Preparation of extracts
 Air dried and coarsely powdered (500 gm) of, Glycyrrhiza glabra root, were placed
in soxhlet extractor separately, using petroleum ether and then successively with
ethanol (70%)
 The extracts were then concentrated to dryness under reduced pressure and
controlled temperature, respectively and they were preserved in a refrigerator
Formula
Ingredients Quantity required (%w/w)
Steric acid 13
Cetyl alcohol 2
Almond oil 4
Glycerol 3
Methyl paraben 0.02
Triethanolamine q.s
Water q.s
Drug extract( Glycyrrhiza glabra) 1.5

Uses of ingredient:
 Glycyrrhiza glabra: it helps in improving skin colour complexion
 Stearic acid: emulsifier, emollient, and lubricant. Also oil soluble
 Cetyl alcohol: thickening agent, soothing the skin
 Almond oil: it provides instant fairness to the dull dry skin and provide glow to skin
 Glycerol: humectant and prevent excessive drying out of the cream
 Methyl paraben and propyl paraben: preservative
 Triethanolamine: used as emulsifier ( to help various ingredients mix better),
neutralizes fatty acids, adjust and buffer the pH

Drug formulation:
 The emulsifier (stearic acid) and other oil soluble components (Cetyl alcohol,
almond oil) were dissolved in the oil phase (Part A) and heated to 75° C
 The preservatives and other water soluble components (Methyl paraban, Propyl
paraban, Triethanolamine, Propylene glycol, all extracts) were dissolved in the
aqueous phase (Part B) and heated to 75° C
 After heating, the aqueous phase was added in portions to the oil phase with
continuous stirring until cooling of emulsifier took place

EXAMPLES OF HARBAL FAIRNESS CREAM
 Himalaya herbals: Natural fairness cream (Key Ingredients: Persian Rose,
Walnut, Aloe Vera, and Mandarin Orange)
 Lotus Herbals White Glow Skin Whitening and Brightening Gel Cream (Key
Ingredients: Mulberry, Grapes)
 Biotique Bio Coconut Skin Whitening and Brightening Cream (Key
Ingredients: Pure Virgin Coconut Water
 Garnier White Complete Speed Cream (Key Ingredient: Pure Lemon Extract)

Evaluation of fairness cream
1.pH of the Cream
 The pH meter was calibrated using standard buffer solution. About 0.5g of the cream
was weighed and dissolved in 50.0 ml of distilled water and its pH was measured
 The pH of the cream base was found to be in range of 6.2-6.9 which is good for skin pH
2.Viscosity:
 Viscosity of the formulation was determined by Brookfield Viscometer at 100 rpm,
using spindle no 7
 The viscosity of cream indicates spreadibilty of cream

3. Dye test
 The scarlet red dye is mixed with the cream
 Place a drop of the cream on a microscopic slide covers it with a cover slip, and
examines it under a microscope
 If the disperse globules appear red the ground colourless. The cream is o/w type
 The reverse condition occurs in w/o type cream i.e. the disperse globules appear
colourless in the red ground

4. Homogeneity
 The formulations were tested for the homogeneity by visual appearance and by
touch
 All formulations of base produce uniform distribution in cream
5. Appearance
 The appearance of the cream was judged by its color, pearlscence and roughness
and graded
 When formulation were kept for long time, it found that no change in colour of
cream base
6. After feel
 Emolliency, slipperiness and amount of residue left after the application of fixed
amount of cream was checked
 Emolliency, slipperiness and amount of residue left after the application of fixed
amount of cream base was found

7. Type of smear
After application of cream, the type of film or smear formed on the skin were checked
After application of cream base, the type of smear formed on the skin were non greasy
8. Removal
The ease of removal of the cream applied was examined by washing the applied part with
tap water
The cream applied on skin was easily removed by washing with tap water
9. Irritancy test
The formulation not to shows any kind of redness, edema, Inflammation and irritation
during irritancy studies
These formulations are safe to use for skin

REFERENCES
1 .Adhirajan N, Dixit VK, Chandrakasan G. Development and evaluation of herbal
formulations for hair growth. Indian Drugs 2001; 38 (11):559-63
2. Bhalearo SS, Salanki NH. Therapeutics approaches to the management of common
baldness. Indian Drugs 2002;39 (1):567-73
3. Bone K. Clinical Applications of Ayurvedic and Chinese Herbs: Monographs for the
Western Herbal Practitioner. Warwick, Queensland: Phytotherapy Press; 1996
4. Cash TF. The psychology of hair loss and its implications for patient care. Clin Dermatol
2001;19(2):161-6.S
5. Bertolino AP. Alopecia areata: A clinical overview. Postgrad Med. 2000;107:81–
90. [PubMed]
6. Olsen EA. Androgenetic alopecia. In: Olsen EA, editor. Disorders of hair growth:
Diagnosis and treatment. New York: McGraw-Hill; 1993. pp. 257–87.

7. Madani S, Shapiro J. Alopecia areata update. J Am Acad
Derm. 2000;42:549–66. [PubMed]
5. Baxley KO, Erdman LK, Henry EB, Roof BJ. Alopecia: Effect on cancer
patient’s body image. Cancer Nurs. 1984;7:499–503. [PubMed]
8. Harrison S, Sinclair R. Optimal management of hair loss (alopecia) in
children. Am J Clin Dermatol. 2003;4:757–70. [PubMed]

COSMECEUTICAL OF HERBAL AND NATURAL ORIGIN

COSMECEUTICAL OF HERBAL AND NATURAL ORIGIN

More Related Content

What's hot

Similar to COSMECEUTICAL OF HERBAL AND NATURAL ORIGIN

Recently uploaded

COSMECEUTICAL OF HERBAL AND NATURAL ORIGIN