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  1. The optimal dosing strategy for recombinant human soluble thrombomodulin (rhTM) in clinical...

    Authors: Tatsuro Kobayashi, Ryusei Mikami and Mineji Hayakawa
    Citation: Thrombosis Journal 2025 23:101
  2. Deep vein thrombosis (DVT) is a serious complication in patients with tibial plateau fractures, yet the association between surgical delay and preoperative DVT risk remains insufficiently explored. This study ...

    Authors: Chao Ling Fan, Wang Chen, Li Jiao Lin, Li Hua Xie and Ming Xiong Li
    Citation: Thrombosis Journal 2025 23:100
  3. Coronavirus Disease 2019 (COVID-19) has been linked to thromboembolic complications, especially in severely ill patients. Intracardiac thrombi are uncommon and pose a very high risk. Coinfection with tuberculo...

    Authors: Maryam Nasiri, Shirin Shakibaei and Sam Zeraatiannejaddavani
    Citation: Thrombosis Journal 2025 23:99
  4. To identify early diagnostic biomarkers for sepsis-induced disseminated intravascular coagulation, we investigated the relationship between the novel coagulation biomarkers and antithrombin with the developmen...

    Authors: Huan Zeng, Jianming Wei, Jiujiang Zeng, Yuexi Sun, Mengmeng Wang, Guoxing Dai and Yanli Song
    Citation: Thrombosis Journal 2025 23:97
  5. The dose of warfarin varies between individuals. Several formulas for predicting the maintenance dose of warfarin have been developed; however, most are complicated and not practical for clinical use.

    Authors: Anunya Ujjin, Natnicha Pongbangli, Wanwarang Wongcharoen, Arisara Suwanagool and Chatree Chai-adisaksopha
    Citation: Thrombosis Journal 2025 23:96
  6. We aimed to evaluate the predictive value of the post-injury D-dimer decrease rate for venous thromboembolism (VTE) in patients with traumatic brain injury (TBI). Additionally, we sought to establish a practic...

    Authors: Chuntao Wang, Mengqi Chen, Kan Wang, Ling Pu, Siyuan Qi, Zhaofeng Kang, Wei Wang, Tao Liu, Weiming Xie, Xiangjun Bai, Zhanfei Li, Xijie Dong and Qiqi Wu
    Citation: Thrombosis Journal 2025 23:95
  7. Antithrombin deficiency (ATD) in pregnant patients significantly increases the risk of venous thromboembolism (VTE), but guidelines for managing anticoagulation during pregnancy, labour, and postpartum in pati...

    Authors: Matija Kozak, Tjaša Vižintin Cuderman, Mojca Božič Mijovski, Miha Lučovnik, Marko Miklič, Gregor Tratar and Tamara Rojnik
    Citation: Thrombosis Journal 2025 23:94
  8. We aimed to ascertain the efficacy of hyperbaric oxygen therapy (HBOT) combined with dual antiplatelet therapy (DAPT) in elderly patients with acute cerebral infarction (ACI) and its impact on nerve factors.

    Authors: Bo Wang, Kai Yu, Jing Wang, Yaoru Li and Meng Li
    Citation: Thrombosis Journal 2025 23:93
  9. Caprini score, the most commonly used assessment tool for predicting postoperative venous thromboembolism (VTE) risk has shown poor predictive value in colorectal cancer surgery. Recent risk assessment models ...

    Authors: Ying Zhang, Ying Zhao, Jun Cai, Lei Niu, Xiaozhu Zhou, Yi Wu, Shicai Chen and Xiangli Cui
    Citation: Thrombosis Journal 2025 23:92
  10. Heparin-induced thrombocytopenia (HIT) is a serious complication associated with heparin use in orthopedic surgery. However, its incidence and risk factors in total knee arthroplasty (TKA) and revision TKA (RT...

    Authors: TingJie Ren, MingCong Chen, QinFeng Yang, SiJia Xu, YuHang Chen, Jian Wang and XuanJian Fu
    Citation: Thrombosis Journal 2025 23:91
  11. Antithrombin, a key regulator of the coagulation cascade, is often decreased in patients with sepsis-associated disseminated intravascular coagulation (DIC). Antithrombin is commonly supplemented when activity...

    Authors: Tomoki Tanigawa, Toshiaki Iba, Cheryl L. Maier, Ecaterina Scarlatescu, Yutaka Kondo, Hideo Wada and Jerrold H. Levy
    Citation: Thrombosis Journal 2025 23:90
  12. Residual chronic obstruction of Pulmonary Embolism (PE) can contribute to pulmonary hypertension and persistent cardiopulmonary limitations. This study comprehensively investigates the influence factors on the...

    Authors: Zhiqiang Liu, Yuanrui Deng, Yan Wu, Xin Gao, Weihua Yin, Lingtao Chong, Jingyu Wang, Lu Hua and Tingting Guo
    Citation: Thrombosis Journal 2025 23:88
  13. Most pulmonary embolism response team (PERT) reports are limited to single hospitals. We evaluated whether process and clinical outcomes differed for patients presenting to pulmonary embolism (PE) referral ver...

    Authors: Anthony J. Weekes, Fernanda Calienes Cerpa, Kelly L. Goonan, Alexa L. Polzella, Melanie M. Hogg, Dalton Cox, Sean Flannigan, Emma Cruz, Halie A. O’Neill, Nathaniel S. O’Connell and Daniel R. Troha
    Citation: Thrombosis Journal 2025 23:87
  14. Cerebrovascular disease (CVD) remains a leading cause of death in the United States. Although the role of conventional stroke risk factors is well established, the impact of coagulation disorders—both inherite...

    Authors: Ibrahim Nagmeldin Hassan, Mohamed Ibrahim, Siddig Yaqub, Muhsin Ibrahim, Haythem Abdalla and Nagmeldin Abuassa
    Citation: Thrombosis Journal 2025 23:86
  15. Bleeding diathesis’ diagnosis can be challenging due to the high number of disorders with hemorrhagic symptomatology. Sitosterolemia is a rare disease characterized by increased sterols plasma levels and cardi...

    Authors: Cristina Marrero-Cepeda, Gloria García-Donas, Francisco Javier Rodríguez-Martorell, Ramiro Núñez-Vázquez, Concepción Prats-Martín, José Antonio Pérez-Simón and María Teresa Vargas
    Citation: Thrombosis Journal 2025 23:84
  16. Angiogenesis inhibitors are vital in cancer treatment but are increasingly linked to thromboembolic events (TEEs), impacting patient outcomes. Despite extensive clinical trials, real-world data on TEEs associa...

    Authors: Jintuo Zhou, Meiling Wu, Tingting Chen, Peiguang Niu, Yanting Zhu, Ying Liu, Huajiao Chen, Xiaoping Zeng and Jinhua Zhang
    Citation: Thrombosis Journal 2025 23:83
  17. Assessing bleeding duration in patients on direct oral anticoagulants (DOACs) is crucial for evaluating reversal strategies, yet no standardized methods are currently available for clinical trials. We investig...

    Authors: Andreas Pfützner, Anne Zimmermann, Sophia Wendling, Julia Jantz, Richard NG Kwet Shing, Jeff Pilot, David Gillen, James C.F. Invest, Nicole Thomé, Claus-Peter Ernst and Brita Willershausen
    Citation: Thrombosis Journal 2025 23:82
  18. Venous thromboembolism (VTE), which includes Pulmonary embolism (PE) and Deep vein thrombosis (DVT), is a complex vascular disorder with poorly understood pathological mechanisms. Emerging research highlights ...

    Authors: Wen Xiao, Danfeng Gu, Mingqi Zhang, Jiansu Liao, Tao Xu, Hailin Lu and Yang Zhao
    Citation: Thrombosis Journal 2025 23:78
  19. Antiphospholipid antibodies (aPLs) are detected in 1–5% of the general population. They include lupus anticoagulant (LAC), anticardiolipin antibodies (aCL) and anti-β2-glycoprotein I antibodies (aβ2GPI). APL i...

    Authors: Weronika Nowak, Joanna Kołodziejczyk-Czepas, Oleksandra Liudvytska, Marzena Tybura-Sawicka, Emilia Krzemińska, Anna Puła and Jacek Treliński
    Citation: Thrombosis Journal 2025 23:77
  20. Protein disulfide isomerase (PDI) catalyzes the reduction, oxidation, and isomerization of disulfide bonds. Although initially discovered as an endoplasmic reticulum (ER)-residing protein, PDI has been demonst...

    Authors: Jinyu Wang, Philip J. Hogg, Xulin Xu and Chao Fang
    Citation: Thrombosis Journal 2025 23:76
  21. The link between venous thromboembolism (VTE) and coronavirus disease 2019 (COVID-19) infection has been consolidated by many studies in the literature. The increased risk of VTE among COVID-19 patients, on th...

    Authors: Tedy Sawma, Joelle Hassanieh, Angie Fares, Hussein Kharroubi, Oussama Issa, Firas Kreidieh and Jamal J. Hoballah
    Citation: Thrombosis Journal 2025 23:75
  22. Thrombosis is a major pediatric health problem with a spectrum of etiologies, clinical presentations, and morbidities. Establishing the diagnosis and treatment of pediatric thrombosis with different site-relat...

    Authors: Galila Mokhtar, Ashraf Abdelbaky, Amira Adly, Dina Ezzat, Hanafy Hafez, Hoda Hassab, Ilham Youssry, Iman Ragab, Laila M. Sherief, Marwa Zakaria, Mervat Hesham, Mervat Mansour, Naglaa shaheen, Tarek Omar, Rasha Abdel-Raouf Abdelaziz Afifi, Sara Makkeyah…
    Citation: Thrombosis Journal 2025 23:74
  23. Pancreatic ductal adenocarcinoma (PDAC) carries a high risk of venous thromboembolism (VTE), which significantly contributes to mortality. However, national trends in VTE-related deaths among this population r...

    Authors: Ibrahim Nagmeldin Hassan, Mohamed Ibrahim, Siddig Yaqub, Muhsin Ibrahim, Haythem Abdalla, Ghada Aljaili, Wafa Osman and Nagmeldin Abuassa
    Citation: Thrombosis Journal 2025 23:73
  24. Recent studies have shown a relation between red blood cell distribution width (RDW) / albumin (RAR) levels and worse outcomes in cases of pulmonary embolism (PE). Simplified pulmonary embolism severity index ...

    Authors: Funda Başyiğit, Emine Cansu Yücel, Oğuz Uçar, Nazlı Turan, Belma Yaman, Arzu Neslihan Akgün, Mustafa Mücahit Balcı and Hatice Tolunay
    Citation: Thrombosis Journal 2025 23:72
  25. Real-world data are needed to inform clinical practice with regards to anticoagulation treatment for persons with venous thromboembolism (VTE).

    Authors: Paraskevi Savvari, Ioannis Skiadas, Evgenia Mavrokefalou, Stavros Kakkos, Ioulia Antoniou, Georgios A. Pitoulias, Effrosyni Dima, Emmanouil Ferdoutsis, Georgios Ntaios, Athanasios Giannoukas, Ourania Kotsiou, Flora Zagouri, Georgios Tsoukalas, Konstantinos Kostikas, Dimitrios Staramos, Haralampos Milionis…
    Citation: Thrombosis Journal 2025 23:71
  26. The mechanism of thrombotic complications in patients with aortic stenosis (AS) is unclear so far. Our aim was to evaluate the levels of phosphatidylserine (PS) exposed on blood cells, endothelial cells (ECs),...

    Authors: Haiyang Wang, Zhaona Du, Yibing Shao, Wei Wu, Dongxia Tong, Fangyu Xie, Jihe Li, Wei Xia and Yujie Zhou
    Citation: Thrombosis Journal 2025 23:70
  27. Effective thromboprophylaxis is critical to reducing mortality and improving clinical outcomes in COVID-19 patients. Despite guidelines recommending prophylactic anticoagulation, particularly for those in inte...

    Authors: Feiya Xu, Yuzhi Tao, Lijun Chen, Yunhui Zhang, Binliang Wang, Jing Han, Chaosheng Deng, Weijia Liu, Guohui Fan, Rui Liang, Zhaofei Chen, Yinong Chen, Kaiyuan Zhen, Yunxia Zhang, Zhu Zhang, Shuai Zhang…
    Citation: Thrombosis Journal 2025 23:69
  28. Acute renal artery embolism (ARAE) is a rare vascular event that precipitates renal infarction (RI) caused by abrupt disruption of renal artery blood flow. RI is frequently misdiagnosed or diagnosed late becau...

    Authors: Long Cheng, Xuanlin Chen, Chongjun Shi, Fanfei Zeng, Weizhong Yang, Huage Cai and Caiyong Lai
    Citation: Thrombosis Journal 2025 23:67
  29. Atherosclerotic plaque regression under lipid-lowering therapy shows considerable individual variation, and the factors influencing this variability remain incompletely understood. This study aimed to investig...

    Authors: Cheng-Hui Fan, Ying Hao, Lyu-Fan Chen, Jing Cheng, Yi-Qiong Wang, Ling-Hao Xu and Ji-Ming Li
    Citation: Thrombosis Journal 2025 23:66
  30. Worldwide, the diagnosis and treatment of immune thrombocytopenia (ITP) and Henoch-Schönlein purpura (HSP) remain a major and ongoing challenge in hematology. Emerging clinical evidences suggest serum mineral ...

    Authors: Yan Chen, Xiuli Hong, Yamei Chen, Zhiqiang Xu and Quanyi Lu
    Citation: Thrombosis Journal 2025 23:65
  31. A considerable number of patients with deep vein thrombosis of the lower extremities will develop post-thrombotic syndrome even after receiving standardized anticoagulation therapy. Damage to the femoral vein ...

    Authors: Dafang Liu, Hui Zhao, Jie Zhang, Liang Zhao and Yingfeng Wu
    Citation: Thrombosis Journal 2025 23:64
  32. Septic-induced coagulopathy (SIC) is a major cause of mortality in sepsis, closely associated with endothelial glycocalyx damage. Enolase 1 (Eno1), a key enzyme in glycolysis, plays a crucial role in sepsis-re...

    Authors: Ke Qin, Xiao Chen, Xiaoling Li, Wenbin Zhang, Xinnan Song, Yuan Wang, Xiaowen Hu and Jianfeng Zhang
    Citation: Thrombosis Journal 2025 23:62
  33. Severe acute respiratory syndrome coronavirus 2 infection causes systemic immune overresponse (cytokine storm), which can lead to microthrombi and dysfunction of coagulation such as disseminated intravascular ...

    Authors: Ryo Hisamune, Kazuma Yamakawa, Noritaka Ushio, Katsunori Mochizuki, Tadashi Matsuoka, Yutaka Umemura, Mineji Hayakawa, Hirotaka Mori, Akira Endo, Takayuki Ogura, Atsushi Hirayama, Hideo Yasunaga, Takashi Tagami, Kohji Okamoto and Akira Takasu
    Citation: Thrombosis Journal 2025 23:61
  34. Mycoplasma pneumoniae pneumonia complicated with arterial embolism in children is rare but progresses rapidly, potentially leading to severe limb ischemia and disability. This study reports a case of MPP complica...

    Authors: Ziyuan Zhang, Yunchao Sun, Jianmin Wang, Xin Zhang, Na Guo, Shaolong Niu and Zening Ma
    Citation: Thrombosis Journal 2025 23:60
  35. Cystic adventitial disease (CAD) is a rare vascular condition that causes arterial stenosis due to the presence of a cyst in the adventitia (outer layer) of the artery. It is most commonly seen in young and mi...

    Authors: Yuheng Wang, Chao Guo, Yi Huang, Xinyang Zhang, Feng Zhu and Dan Shang
    Citation: Thrombosis Journal 2025 23:59
  36. Locally acting antiplatelet and anticoagulant (APAC) is developed as an antithrombotic agent for administration during vascular interventions and in thrombo-inflammatory conditions. APAC has entered human stud...

    Authors: Zsuzsa Bagoly, Annukka Jouppila, Rita Orbán-Kálmándi, Linda Lóczi, Dóra Bomberák, Zsófia Anna Kádár, Ádám Deák, Ádám Mátrai, Ildikó Beke Debreceni, János Kappelmayer, Norbert Németh and Riitta Lassila
    Citation: Thrombosis Journal 2025 23:57
  37. Coagulation defects, including purpura and other haemorrhagic conditions, are a critical area of medical research because of their significant health effects worldwide. Understanding the metabolic basis of the...

    Authors: Jiaqi Wei, Zhen Yang, Xiaojin Wu, Nana Zheng and Depei Wu
    Citation: Thrombosis Journal 2025 23:55
  38. Venous thromboembolism (VTE) is a significant global health issue, yet effective therapeutic targets for its prevention and treatment remain elusive. This study aimed to identify plasma proteins causally assoc...

    Authors: Xiaolong Li, Cheng-hao Yang, Min Zhou and Min-yi Yin
    Citation: Thrombosis Journal 2025 23:54
  39. Deep venous thrombosis (DVT) is part of a spectrum of venous thromboembolism, which also includes pulmonary embolism. Up to 50% of hospitalized individuals who develop pulmonary embolism have DVT. Pulmonary em...

    Authors: Robert Bizaleri Baluku, Faith Ameda, Eva Nabawanuka and Christine Sekaggya-Wiltshire
    Citation: Thrombosis Journal 2025 23:53

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  • Thrombosis Journal is the official journal of the Asian-Pacific Society on Thrombosis and Hemostasis.

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