Epilepsy articles from across Nature Portfolio

This study used accelerometer data from participants of the UK Biobank to reveal associations between sedentary and physical activity levels and mortality in people with epilepsy. These associations differ between people with epilepsy and the general population.

Infectious diseases can cause acute seizures. Here the authors investigate their long-term impact on the risk of epilepsy for older adults. They find that hospital-treated infectious diseases have a lasting impact on the development of epilepsy in older age, and that cardiovascular risk factors may exacerbate this impact.

Over 50 million people worldwide suffer from epilepsy, and many patients remain resistant to medication. Here, the authors hypothesized that targeting thalamic nuclei with precise anatomical and functional connections to SOZ (hodological matching) can enhance neuromodulatory effects in focal epilepsy.

Whether and how gamma entrainment using sensory stimuli (GENUS) has a role in antiepileptogenesis is not fully understood. Here authors show that GENUS reduces seizure susceptibility in male mice. These effects are mediated via specific visual neural pathway.

Status epilepticus is associated with changes in metabolic pathways, a new study has shown.

Brain somatic mosaicism is linked to several neurological disorders and is thought to arise post-zygotically. A study suggests that pre-zygotic aneuploidy followed by post-zygotic partial reversion leads to a recurrent form of brain mosaicism-related epilepsy.