A lemur in a tree

Multiple bursts of speciation in Madagascar’s endangered lemurs

Kathryn Everson and colleagues explore lemur evolution using a phylogenomic dataset with broad taxonomic sampling, revealing patterns of speciation, extinction, and gene flow.

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  • Understanding the impact of the solid electrolyte interphase (SEI) on lithium deposition is crucial for developing high-energy lithium metal batteries. Here, authors elucidate the multi-scale effects of the SEI on lithium deposition behavior based on the established SEI-omics framework.

    • Gongxun Lu
    • Zhiyuan Han
    • Guangmin Zhou
    ArticleOpen Access
  • Constructing synthetic mimics of membraneless organelles using small molecules can contribute towards our understanding of active phase separation and their role in the chemical emergence of compartments. Herein, the authors develop a model of synthetic membraneless organelles as non-equilibrium droplet phase which are accessed via homotypic interactions between small activated molecule and short peptides.

    • Saurabh Gupta
    • Sangam Jha
    • Dibyendu Das
    ArticleOpen Access
  • Traditional relaxor ferroelectrics are rooted in crystalline systems, motivating exploration of their fluidic analogues through engineered polar nanoregions in dielectric nematic environments. Authors report a nematic relaxor ferroelectric that shows field-induced polarization and tunable energy landscapes, revealing stable high-temperature relaxor behavior and low-temperature field-induced ferroelectric transitions.

    • Xinxin Zhang
    • Yu Zou
    • Mingjun Huang
    ArticleOpen Access
  • COâ‚‚ hydrogenation on Cu/Alâ‚‚O₃ is limited by low activity. Herein, high-velocity gas collisions create transient distorted Cu sites, tripling COâ‚‚ conversion, boosting methanol selectivity to 95 % and increasing the space-time-yield six times.

    • Zhewei Zhang
    • Jun Yao
    • Weiping Ding
    ArticleOpen Access

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  • Machine learning (ML) is rapidly influencing the development of many research areas, including biocatalysis, the use of enzymes and living systems to mediate chemical reactions, often of pharmaceutical and industrial importance. To find out how can machine learning be applied to biocatalysis research, we talked to three scientists, Professor Rebecca Buller (Zurich University of Applied Sciences), Dr. Stanislav Mazurenko (Masaryk University) and Associate Professor Yang Yang (University of California, Santa Barbara). We discussed the potentials and challenges associated with ML, how collaborations between computational and biocatalysis experts can be promoted, and how will the field develop in the future.

    Q&AOpen Access
  • Transforming agricultural landscapes to be more sustainable and resilient requires integrated and multidisciplinary approaches. Linking automated experimental platforms with living labs can accelerate knowledge gain, enhance interdisciplinary collaboration, and support real-world change by addressing key challenges in current agricultural systems.

    • Mathias Hoffmann
    • Cheng Chen
    • Maren Dubbert
    CommentOpen Access
  • In a recent study, Park et al. show that early-life loss of NR3C1 in astrocytes establishes a long-lasting epigenetic memory that heightens neuroinflammation and worsens pathology in the central nervous system (CNS) later in life. These findings highlight the potential roles of astrocyte inflammatory memory in CNS pathology, as well as potential targets for its modulation.

    • Hong-Gyun Lee
    • Francisco J. Quintana
    CommentOpen Access
  • The preclinical exploration of nanomedicine for cancer theranostics is rapidly expanding, underscoring its significant translational potential. The diverse physicochemical properties of these nanosystems — including size, morphology, surface charge, hydrophobicity, catalytic activity, and chirality — inevitably influence their interactions with biological systems. As a result, comprehensive biological validation and interdisciplinary collaboration across fields such as biochemistry, biomedical engineering, pharmacology, immunology, and oncology are essential.

    Q&AOpen Access
  • The consequences of weather and climate extremes are felt disproportionately by some of the most disadvantaged populations of the world. Gaps in data and research perpetuate these deeply rooted inequalities and must be overcome.

    EditorialOpen Access
  • Microscopy drives biological discovery, yet high costs limit its access to resource-limited regions. We highlight examples of successful frugal microscopes that have overcome adoption barriers, offering a roadmap to expand affordable, quantitative imaging tools and foster impactful research in resource-limited settings.

    • Mai A. Rahmoon
    • Chad M. Hobson
    • Jesse S. Aaron
    CommentOpen Access
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