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Game Details
Regular Season
FOX
Bank of America Stadium
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Schedule
Panthers
CAR
4-3
Bills
BUF
4-2
View game
FOX
Panthers
CAR
4-3
Packers
GB
4-1-1
View game
FOX
Panthers
CAR
4-3
Saints
NO
1-6
View game
FOX
Panthers
CAR
4-3
Falcons
ATL
3-3
View game
FOX
Panthers
CAR
4-3
49ers
SF
5-2
View game
ESPN
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Schedule
Bills
BUF
4-2
Panthers
CAR
4-3
View game
FOX
Bills
BUF
4-2
Chiefs
KC
4-3
View game
CBS
Bills
BUF
4-2
Dolphins
MIA
1-6
View game
CBS
Bills
BUF
4-2
Buccaneers
TB
5-2
View game
CBS
Bills
BUF
4-2
Texans
HOU
2-4
View game
AMZN
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Buffalo
Bills
BUF
4-2
Carolina
Panthers
CAR
4-3
FOX
59° F
BUF -7.5, O/U 45.5
Game
Stats
Odds
Videos
What Young's likely Week 8 absence means for CAR
What Young's likely Week 8 absence means for CAR
NBC Sports
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Rapoport: Bryce Young (ankle) expected to miss Week 8 game vs. Bills 'Up to the Minute'
Rapoport: Bryce Young (ankle) expected to miss Week 8 game vs. Bills 'Up to the Minute'
NFL Highlights
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Take Dalton, Panthers to cover spread vs. Bills
Take Dalton, Panthers to cover spread vs. Bills
NBC Sports
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Buffalo Bills Primed for Victory Over Carolina Panthers
Buffalo Bills Primed for Victory Over Carolina Panthers
SportsGrid
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Who is Panthers' backup QB if Bryce Young is out with ankle injury?
Ryan Miller, Rochester Democrat and Chronicle
Carolina Panthers Add QB After Bryce Young Injury
Andrew Buller-Russ
Panthers release initial depth chart for Week 8 matchup vs. Bills
Anthony Rizzuti, Panthers Wire
Top Headlines
Who is Panthers' backup QB if Bryce Young is out with ankle injury?
Ryan Miller, Rochester Democrat and Chronicle
Carolina Panthers Add QB After Bryce Young Injury
Andrew Buller-Russ
Panthers release initial depth chart for Week 8 matchup vs. Bills
Anthony Rizzuti, Panthers Wire
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Game Details
Regular Season
FOX
Bank of America Stadium
Stat Leaders
Passing Yards
1397 Yds
1288 Yds
Rushing Yards
537 Yds
551 Yds
Receiving Yards
287 Yds
413 Yds
Sacks
2.0 Sack
3.0 Sack
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Odds
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Odds by
Spread
Spread
Total
Total
Money Line
Money
Buffalo Bills
BUF
-7.5
O 45.5
-400
Carolina Panthers
CAR
+7.5
U 45.5
+310
Injuries
Buffalo Bills
View All
DaQuan Jones
Defensive Tackle
Q
10/21/25
Calf
Curtis Samuel
Wide Receiver
Q
10/21/25
Neck
Matt Milano
Linebacker
Q
10/21/25
Pectoral
Carolina Panthers
View All
David Moore
Wide Receiver
IR
10/21/25
Elbow
Robert Hunt
Guard
IR
10/21/25
Biceps
Damien Lewis
Guard
Q
10/21/25
Shoulder
Bills
Panthers
Buffalo Bills
View All
DaQuan Jones
Defensive Tackle
Q
10/21/25
Calf
Curtis Samuel
Wide Receiver
Q
10/21/25
Neck
Matt Milano
Linebacker
Q
10/21/25
Pectoral
Team Comparison
Bills
Offense
Panthers
27.8
Points per Game
20.7
4th
24th
389.2
Total Offensive Yards per Game
341.0
3rd
20th
238.2
Passing Yards per Game
200.9
13th
28th
151.0
Rushing Yards per Game
140.1
1st
3rd
33:12
Time of Possession per Game
32:33
1st
3rd
41.2
3rdD%
37.4
11th
21st
Bills
Defense
Panthers
22.8
Points Allowed per Game
21.7
17th
14th
323.5
Total Yards Allowed per Game
295.7
15th
7th
167.2
Passing Yards Allowed per Game
203.1
2nd
10th
156.3
Rushing Yards Allowed per Game
92.6
31st
8th
15
Sacks
11
14th
28th
2
Interceptions
6
24th
8th
Offense
Defense
Bills
Offense
Panthers
27.8
Points per Game
20.7
4th
24th
389.2
Total Offensive Yards per Game
341.0
3rd
20th
238.2
Passing Yards per Game
200.9
13th
28th
151.0
Rushing Yards per Game
140.1
1st
3rd
33:12
Time of Possession per Game
32:33
1st
3rd
41.2
3rdD%
37.4
11th
21st
Recent Games
Buffalo Bills
View All
Mon, 10/13
@
ATL
L
14
24
Mon, 10/6
vs
NE
L
20
23
Sun, 9/28
vs
NO
W
31
19
Fri, 9/19
vs
MIA
W
31
21
Sun, 9/14
@
NYJ
W
30
10
Carolina Panthers
View All
Sun, 10/19
@
NYJ
W
13
6
Sun, 10/12
vs
DAL
W
30
27
Sun, 10/5
vs
MIA
W
27
24
Sun, 9/28
@
NE
L
13
42
Sun, 9/21
vs
ATL
W
30
0
Schedule
Schedule
27.8
20.7389.2341.0238.2200.9151.0140.133:1232:3341.237.4
