T-helper 2 cells

Latest research

1. Expansion of peripheral helper T cells in the peripheral blood of patients with chronic graft-versus-host disease

   • Yuanyuan Du
   • Xuefeng He
   • Yuejun Liu

   in Annals of Hematology

   Article Open access 03 November 2025

   

2. Targeting CXCR2 in prostate cancer cells can block CD47-SIRPα interaction and reverse M2 macrophage polarization in the TME

   • Yi Sun
   • Shangqing Ren
   • Ju Guo

   in Molecular Cancer

   Article Open access 30 October 2025

   

3. ILC2s in the nerves

   • Ioana Staicu

   in Nature Immunology

   Article 29 October 2025

4. Feeling exhausted, no longer – macrophages keep type 2 innate lymphoid cells energized

   • Megan Kinzel
   • Dalia Ibrahim
   • Nicolas Jacquelot

   in Cellular & Molecular Immunology

   Article 27 October 2025

   

5. Stage-specific roles of clonally expanded CD8⁺ T cells in regulating amyloid pathology in Alzheimer’s disease models

   • Masaki Ohyagi
   • Minako Ito
   • Akihiko Yoshimura

   in Nature Communications

   Article Open access 27 October 2025

   

6. A co-stimulatory signal via the coinhibitory TIGIT

   • Kazuko Shibuya
   • Akira Shibuya

   in Nature Immunology

   Article 24 October 2025

   

7. Generation of the augmented IL-15-secreting anti-HER2 chimeric antigen receptor (CAR)-NK cells: an encouraging immunotherapeutic tool

   • Reza Darvishvand
   • Maryam Asadi
   • Nasrollah Erfani

   in Molecular Biology Reports

   Article 23 October 2025

   

8. Psoriasis and lichen planus: an immunohistochemical study of Trophoblast cell-surface antigen 2 expression in skin biopsies

   • Giovanni Tossetta
   • Sonia Fantone
   • Daniela Marzioni

   in Human Cell

   Article 23 October 2025

   

9. Single-cell RNA profiling of blood CD4⁺ T cells identifies distinct helper and dysfunctional regulatory clusters in children with SLE

   • Preetha Balasubramanian
   • Uthra Balaji
   • Simone Caielli

   in Nature Immunology

   Article 21 October 2025

   

10. Solutions of the fractional-order HIV infection system of T-cells by exploiting a radial basis neural network procedure

    • Ayse Nur Akkilic
    • Muhammad Umar
    • Hasan Bulut

    in The European Physical Journal Plus

    Article 21 October 2025

    

11. Breastfeeding boosts immune cells that protect against breast cancer

    • Starre Vartan

    in Nature

    Article 20 October 2025

    

12. αTIGIT-IL2 achieves tumor regression by promoting tumor-infiltrating regulatory T cell fragility in mouse models

    • Tianci Wang
    • Yupu Xu
    • Xiaohu Zheng

    in Nature Communications

    Article Open access 17 October 2025

    

13. Treg cells mitigate inflammatory responses and symptoms via β2-AR/β-Arr2/ERK signaling in an experimental rheumatoid arthritis

    • Yan Liu
    • Xiao-Qin Wang
    • Yu-Ping Peng

    in Arthritis Research & Therapy

    Article Open access 17 October 2025

    

14. Heme and iron toxicity in the aged spleen impairs T cell immunity through iron deprivation

    • David Ezuz
    • Heba Ombashe
    • Noga Ron-Harel

    in Nature Aging

    Article Open access 17 October 2025

    

15. Th1 and Th2 cells in equine endometrosis and their interactions with endometrial fibroblasts

    • Anna Wójtowicz
    • Agnieszka Sadowska
    • Anna Szóstek-Mioduchowska

    in Scientific Reports

    Article Open access 16 October 2025

    

16. The co-inhibitory receptor TIGIT promotes tissue-protective functions in T cells

    • Camilla Panetti
    • Rahel Daetwyler
    • Nicole Joller

    in Nature Immunology

    Article Open access 15 October 2025

    

17. Lipid-Metabolically Active TREM2^high Microglia‑Derived Macrophages Predict Poor Prognosis and Represent an Immunotherapeutic Target in Glioma

    • Jinxin Li
    • Xiaotong Yu
    • Yan Wang

    in Journal of Neuroimmune Pharmacology

    Article 14 October 2025

    

18. Neue Daten zur Versorgung von Menschen mit TK2d

    • Redaktion Facharztmagazine

    in Pädiatrie

    Article 13 October 2025

19. Medizin

    • Redaktion Facharztmagazine

    in CME

    Article 13 October 2025

    

20. Annexin A2 facilitates porcine circovirus type 2 infection by mediating viral attachment to host cells and interacting with the capsid protein

    • Yifan Jiang
    • Xinnuo Lei
    • Naidong Wang

    in Veterinary Research

    Article Open access 10 October 2025

    

Related journals

• 

  Journal

  Nature Immunology

  Nature Immunology, ranked first out of more than 100 primary immunology research journals, brings together the most significant immunology research...

  Publishing model

  Hybrid

  Journal Impact Factor

  27.6 (2024)

  Downloads

  5,636,301 (2024)

  Submission to first decision(median)

  4 days

• 

  Journal

  Nature Reviews Immunology

  Immunology is a diverse and growing discipline that can be defined as the study of the tissues, cells and molecules involved in host defence...

  Publishing model

  Subscription

  Journal Impact Factor

  60.9 (2024)

  Downloads

  4,827,554 (2024)

  Submission to first decision(median)

  9 days

• 

  Journal

  Cancer Immunology, Immunotherapy

  Since its inception in 1976, Cancer Immunology, Immunotherapy(CII) has reported significant advances in the field of tumor immunology. The journal...

  Publishing model

  Open Access

  Journal Impact Factor

  5.1 (2024)

  Downloads

  1,507,571 (2024)

  Submission to first decision(median)

  3 days