Protein Folding

Latest research

1. RNA inverse folding can be solved in linear time for structures without isolated stacks or base pairs

   • Théo Boury
   • Samuel Gardelle
   • Yann Ponty

   in Algorithms for Molecular Biology

   Article Open access 24 October 2025

   

2. Navigating the landscape of protein folding and proteostasis: from molecular chaperones to therapeutic innovations

   • Omer Faruk Kuzu
   • Lars Jørgen Tvenge Granerud
   • Fahri Saatcioglu

   in Signal Transduction and Targeted Therapy

   Article Open access 23 October 2025

   

3. Investigating whether deep learning models for co-folding learn the physics of protein-ligand interactions

   • Matthew R. Masters
   • Amr H. Mahmoud
   • Markus A. Lill

   in Nature Communications

   Article Open access 06 October 2025

   

4. Generalized design of sequence–ensemble–function relationships for intrinsically disordered proteins

   • Ryan K. Krueger
   • Michael P. Brenner
   • Krishna Shrinivas

   in Nature Computational Science

   Article 06 October 2025

   

5. Multiscale theoretical study of infrared spectroscopy for the thermal denaturation process of aprotinin

   • Wei Xiang
   • Jianjie Xu
   • Yunfan Yang

   in Journal of Molecular Modeling

   Article 04 October 2025

   

6. How SecB maintains clients in a translocation competent state

   • Guillaume Roussel
   • Jochem H. Smit
   • Anastassios Economou

   in Communications Biology

   Article Open access 03 October 2025

   

7. Hypertrophic cardiomyopathy mutations Y115H and E497D disrupt the folded-back state of human β-cardiac myosin allosterically

   • Neha Nandwani
   • Debanjan Bhowmik
   • Kathleen M. Ruppel

   in Nature Communications

   Article Open access 01 October 2025

   

8. Propeptide-mediated enhancement of hyperthermophilic subtilisin-like protease expression in Escherichia coli

   • Ryo Uehara
   • Shuto Nishizaki
   • Shun-ichi Tanaka

   in AMB Express

   Article Open access 26 September 2025

   

9. Biomarkers and Therapeutical Targets for Prion Diseases

   • Giuseppe Legname
   • Fabio Moda

   in Subcellular Biochemistry

   Book 2025

   

10. FE prediction of folding defects in axisymmetric plate forging process

    • Zhihang Xie
    • Wenzheng Dong
    • Zhigang Wang

    in The International Journal of Advanced Manufacturing Technology

    Article 22 September 2025

    

11. The human ribosome modulates multidomain protein biogenesis by delaying cotranslational domain docking

    • Grant A. Pellowe
    • Tomas B. Voisin
    • David Balchin

    in Nature Structural & Molecular Biology

    Article Open access 19 September 2025

    

12. Decoding pH-dependent structural dynamics of CHIKV nsP2 protease: insights from computational antiviral targeting

    • Rubha Shri Gurunathan
    • Abhirami Rajaram
    • Sanjeev Kumar Singh

    in Molecular Diversity

    Article 16 September 2025

    

13. ¹H, ¹⁵N, and ¹³C resonance assignment of human heat shock protein 10

    • Abigail Page
    • Wyatt Hendricks
    • Marielle A. Wälti

    in Biomolecular NMR Assignments

    Article Open access 13 September 2025

    

14. Charged peptides enriched in aromatic residues decelerate condensate ageing driven by cross-β-sheet formation

    • Ignacio Sanchez-Burgos
    • Andres R. Tejedor
    • Jorge R. Espinosa

    in Nature Communications

    Article Open access 28 August 2025

    

15. Phosphorylation toggles the SARS-CoV-2 nucleocapsid protein between two membrane-associated condensate states

    • Bruna Favetta
    • Huan Wang
    • Benjamin S. Schuster

    in Nature Communications

    Article Open access 26 August 2025

    

16. Visualizing dynamic tubulin folding in chaperonin TRiC from nonnative nucleus to final native state

    • Yanyan Zhao
    • Michael F. Schmid
    • Wah Chiu

    in Nature Communications

    Article Open access 23 August 2025

    

17. Discovery of a multi-chaperone condensate in the endoplasmic reticulum

    in Nature Cell Biology

    Article 20 August 2025

    

18. Effects of ultrasonic pretreatment on the structure, solubility and thermal stability of transglutaminase cross-linked black bean protein isolate

    • Yuejiao Xing
    • Yue San
    • Li Zheng

    in Journal of Food Measurement and Characterization

    Article 20 August 2025

    

19. Co-translational ribosome pairing enables native assembly of misfolding-prone subunits

    • Florian Wruck
    • Jaro Schmitt
    • Sander J. Tans

    in Nature Communications

    Article Open access 15 August 2025

    

20. The topological properties of the protein universe

    • Christian D. Madsen
    • Agnese Barbensi
    • Michael P. H. Stumpf

    in Nature Communications

    Article Open access 13 August 2025

    

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