Alcohol Induced Alterations to the Human Fecal VOC Metabolome
Fig 6
Fold change analysis of the metabolite abundance between the healthy and alcoholic fecal samples.
The fold change (FC) is calculated as the log transformation of the ratio between the mean metabolite abundance in the alcoholic cohort relative to the healthy cohort. The analysis was performed with both the endoscopy (A) and home passage collected (B) metabolomes. A log2(FC) greater than 1.5 is deemed significant (equivalent to a threefold or greater change in metabolite abundance). A fold change analysis comparing median analyte values produces similar results (not shown).