Modulation of Macrophage Activation State Protects Tissue from Necrosis during Critical Limb Ischemia in Thrombospondin-1-Deficient Mice
Figure 4
Postischemic angiogenesis is increased in tsp-1−/− mice.
(A&B) Capillary density of gastrocnemius muscle sections was assessed at d4 using CD31 immunostaining in tsp-1−/− (A) and wt (B) mice (scale bar = 500 µm). (C&D) CD31 immunostaining of infiltrated area in tsp-1−/− (C) and wt (D) mice; scale bar = 200 µm. (E) Quantification of capillary density in the different area types in gastrocnemius muscles, d4 after ischemia. Mean±SEM are shown. * = p<0.05; ** = p<0.01; n = 9.