A Quantitative Systems Approach Reveals Dynamic Control of tRNA Modifications during Cellular Stress
Figure 4
Phenotypic analysis of cytotoxicity induced by MMS, NaOCl, H2O2, and NaAsO2 in yeast mutants lacking trm tRNA methyltransferase and other modification genes.
Data represent mean ± SD for three biological replicates. Asterisks denote values statistically different from unexposed controls by Student's t-test, p<0.05. Associated RNA modifications are listed below each enzyme.