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  • Collection |

    The 2025 Nobel Prize in Physiology or Medicine has been awarded jointly to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance”.

    Image: Springer Nature/The Nobel Foundation/Imagesource
  • Focus |

    Ageing is a fundamental driver of cancer, fostering the accumulation of genetic and epigenetic changes that disrupt cellular homeostasis, promote immune system decline, alter systemic metabolism and increase cellular senescence.

    Image: L. Crow/Springer Nature Ltd.
  • Collection |

    The gut microbiome plays a crucial role in cancer development and progression, by influencing the host immune system and metabolism.

    Image: L. Crow/Springer Nature Ltd.
  • Collection |

    The field of cancer metabolism research is entering its 2nd century since the first description of the changes in metabolism of cancer cells by Otto Warburg and his colleague Seigo Minami in 1923.

    Image: Lara Crow/Springer Nature Limited
  • Collection |

    The Nobel Prize in Physics 2024 has been awarded to John J. Hopfield and Geoffrey E. Hinton “for foundational discoveries and inventions that enable machine learning with artificial neural networks”.

    Image: Springer Nature/The Nobel Foundation/Imagesource
  • Collection |

    The 2024 Nobel Prize in Physiology or Medicine has been awarded jointly to Victor Ambros and Gary Ruvkun "for the discovery of microRNA and its role in post-transcriptional gene regulation".

  • Series |

    In this Series we present specially commissioned articles that discuss the key issues and our current knowledge of the role of tumour suppressors and oncogenes in cancer.

    Image: L. Crow/Springer Nature Ltd.
  • Collection |

    The 2023 Nobel prize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their “discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19”.

    Image: Springer Nature/The Nobel Foundation/Imagesource
  • Series |

    Sex differences begin at fertilization and affect nearly all body systems during development.

    Image: Lara Crow/Springer Nature Limited
  • Collection |

    Cancer is a leading cause of death, accounting for nearly one in six deaths worldwide. Many cancers can be cured, especially if detected early and treated effectively.

    Image: Kateryna Lon/ Science Photo Library/ Getty Images
  • Collection |

    Selected, recent articles from across the Nature Portfolio that document the recent progress in understanding the biology of EV-mediated cell–cell communication and advances in clinical translation of EVs.

    Image: Vicky Summersby
  • Collection |

    One of the fundamental biological processes in life is the cell cycle leading from DNA replication to cell division. While it has been studied for decades and our knowledge has matured, sophisticated experimental approaches have rejuvenated the field. In addition, cell cycle regulators have emerged as cancer therapy targets. This collection showcases ground-breaking cell cycle papers and reviews, ranging from basic discoveries to clinical applications.

    Image: Nicolas Plachta, NCB (2022)

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