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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Combining sodium-glucose co-transporter-2 inhibitor with mesenchymal stem cells and brown adipose tissue (BAT) and white adipose tissue (WAT) transplantation to mitigate the progression of diabetic kidney disease: a pre-clinical approach

Fig. 1
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Metabolic and renal functional parameters in the experimental groups. A Schematization of the treatment protocols. Conditioning of the groups receiving calorie restriction and initiation of empagliflozin in the chow for SGLT2i-tretaed gropus occurred at 4–5 weeks of age. In the groups receiving combined therapy with BM-MSC, injections were administered at the 8th and 10th weeks of age. Euthanasia was performed at 14–15 and 18–20 weeks of age. B Body weight variation. C Estimated glomerular filtration rate (eGFR) normalized by body weight. D Urinary volume in mL. E Albumin measured in μg/mL over time. F Natriuresis normalized by creatinuria. G Glycosuria normalized by creatinuria. (*p < 0.05). Error bars represent mean ± SEM; n = 6–12 animals

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Stem Cell Research & Therapy

ISSN: 1757-6512