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Articles

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  1. To date, Despite the widespread and mature clinical application of fracture treatment techniques, a large number of patients still suffer from nonunion due to impaired bone regeneration function. In the past f...

    Authors: Kechi Li, Guoxiang Liu, Feiyu Chen, Xiaolong Sun and Bin Liu
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:924
  2. Distal femoral fractures, comprising 0.4% of all fractures, present significant management challenges due to their complex anatomy and associated complications. While single plating (SP) is commonly used, its ...

    Authors: Ahmed Oun, Hamdy Khaled Sabra, Omar Abdelaziz, Islam Saeed Elhois, Ahmad Omar Saleh, Khaled Hemdan and Ahmed O. Sabry
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:923
  3. Surgical intervention is the preferred approach to prevent further progression of deformity for patients with adolescent idiopathic scoliosis (AIS); among existing surgeries, posterior spinal fusion is predomi...

    Authors: Zhengye Zhao, Aoran Maheshati, Xueyi Zhang, Di Liu, Terry Jianguo Zhang and Nan Wu
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:921
  4. Owing to the common but reductive practice of aggregating heterogeneous robotic systems without accounting for navigation integration or technological iteration, existing classifications hinder the comparabili...

    Authors: Yixi Wang, Yang Xiao, Jingjie Wang, Paerhati Rexiti and Yang Wang
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:920
  5. The direct anterior approach (DAA) for total hip arthroplasty is increasingly adopted because of its muscle-sparing nature and potential for faster recovery. However, its use is often limited by the need for a...

    Authors: Raffaele Iorio, Federico Corsetti, Simone Fenucci, Edoardo Viglietta, Yuri Gugliotta, Filippo Migliorini and Nicola Maffulli
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:919
  6. The use of an intramedullary (IM) or extramedullary (EM) tibial cutting guide in total knee arthroplasty (TKA) is debated. This study critically analyses our experience using the IM tibial cutting guide for TKA.

    Authors: Gennaro Pipino, Francesco Anzano, Enzo Claudio Moretti, Raffaele Borghi, Davide Corrado Vaccarisi, Patrizio Caldora, Bruno Violante, Nicola Maffulli, Filippo Migliorini and Vincenzo Salini
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:918
  7. Anteverted pelvis (AP) subgroup is unusual subtype in asymptomatic population characterized by low pelvic incidence (PI), high lumbar lordosis (LL), and a sloped sacrum. However, the contribution of paraspinal...

    Authors: Yi Zhao, Siyu Zhou, Yudong Zhao, Zhuoran Sun and Weishi Li
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:917
  8. Knee osteoarthritis (KOA) is the primary cause of lower-limb disability and poses a substantial socio-economic burden. This systematic review and meta-analysis aims to assess the prevalence of KOA in the Chine...

    Authors: Xin Chen, Changli Shao, Li Li, Zheng Zuo and Yan Wang
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:916
  9. Compartmental imbalance in proximal tibial bone density may contribute to the structural progression of knee osteoarthritis (OA), yet remains underexplored using quantitative imaging. This study investigated t...

    Authors: Hogyeong Kang, Geonil Kim, Sungjoon Lim and Soonchul Lee
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:915
  10. Pedicle screw fixation is commonly used in spinal surgery; however, screw loosening is a frequent complication, and adversely affects both surgical outcomes and patient prognosis. This review focuses on pedicl...

    Authors: Qinfan Wu, Jiahu Huang and Yun Cao
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:914
  11. Previous studies have demonstrated a close association between knee joint anatomical features and lesions of the anterior cruciate ligament (ACL) and meniscus. However, the anatomical risk factors specifically...

    Authors: Shuai Xu, Meifeng Lu, Sisi Zhang, Gaobing He, GuiHao Zheng, Yulong Ouyang and Guicai Sun
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:912
  12. Tendon injury is one of the most frequently encountered soft tissue injuries with slow repair and poor functional recovery. Over the past few years, there’s been a buzz about how exosomes might boost tissue re...

    Authors: Liu Chunbo, Li Jia, Zhang Jian, Gao Yaxian, Guan Chenwei and Xu Cong
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:911
  13. The objective study was to compare medial tibial stress variations in three different situations: (1) on native knees, (2) after performing medial meniscus ramp lesions then (3) after their arthroscopic treatm...

    Authors: Mathieu Severyns, François Zot, Tanguy Vendeuvre, Jean-Baptiste Marchand, Valery Valle and Arnaud Germaneau
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:910
  14. The ideal treatment of osteochondral defects is controversial. Regenerative treatment methods aim to produce ideal scaffolds using different biomaterials. Decellularized extracellular...

    Authors: Melih Oral, Emin Suha Dedeogullari, Selin Onen, Cansu Ozdemir, Bihter Muratoglu, Zeynep Caglar, Halil Murat Aydin, Duygu Uckan Cetinkaya, Petek Korkusuz and Egemen Turhan
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:909
  15. Periprosthetic joint infection (PJI) is a severe complication of arthroplasty. Surgical helmet system (SHS) was introduced to reduce airborne contamination however their efficacy remains controversial. This sy...

    Authors: Tan Qing Hang, Amirzeb Aurangzeb, Omar Mohamed Hussein El Dishish, Charles Kon Kam King and Moo Ing How
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:908
  16. To introduce a new classification of calcified lumbar disc herniation (CLDH), and to evaluate the clinical performance of the unilateral biportal endoscopic technique (UBE) in treating CLDH.

    Authors: Hao Liu, Xiang Yang, Heng Wu, Shuai Zhang and Song Wang
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:907
  17. Combined anterior cruciate ligament (ACL) and medial collateral ligament (MCL) injury is the most common combination of ligamentous knee injury. Many authors support the conservative treatment of MCL tears. Th...

    Authors: Mohammad Razi, Mohammad Soleimani, Haleh Dadgostar and Saeed Razi
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:906
  18. Traditional surgical options for releasing stiff elbows include open and arthroscopic techniques. The former involves long incisions and significant surgical trauma, while the latter is technique-demanding and...

    Authors: Hongru Ma, Lingzhe Xuan, Zhenjia Zhong, Zitao Zhang, Zezhang Zhu, Yong Qiu and Fengfeng Li
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:905
  19. Osteosarcoma (OS), the most prevalent primary malignant bone tumor in adolescents, demonstrates aggressive clinical behavior and poor prognosis. This study aimed to elucidate the functional role and molecular ...

    Authors: Xiaofei Shen, Guoyou Zou, Zhengchun Cao and Huanxiang Bao
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:904
  20. The boutonniere deformity of the digit, resulting from a flexion deformity of the proximal interphalangeal joint (PIPJ) and an extension deformity at the distal interphalangeal joint, is a well-documented cond...

    Authors: Giovanni F. Solitro, Diego Barragan Echenique, Mark H. Gonzalez and Farid Amirouche
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:903
  21. Osteoblast formation and function are essential for regulating bone disorders such as osteoporosis. Recent studies have confirmed that long non-coding RNAs (lncRNAs) from exosomes (ExOs) are involved in osteob...

    Authors: Hui Sun, Yibin Liu, Haoran Wang, Zhiqiang Ma, Fang Xu, Xinlian Li and Gang Lv
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:902
  22. This study aims to systematically review and analyze the clinical and radiographic outcomes of high tibial osteotomy (HTO) combined with various bone defect filler materials for the treatment of medial compart...

    Authors: Zhiwei Pei, Aixian Tian, Baoxin Zhang, Zijian Lian and Xinlong Ma
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:901
  23. Oblique lumbar interbody fusion with anterolateral screw fixation (ASF) has been used to treat lumbar degenerative disease. Cage subsidence, a common OLIF complication, is significantly affected by low bone mi...

    Authors: Jiacheng Jin, Zhuhai Li, Xiaoping Mu, Jiahong Nong, Xiaodong Wei, Fuyu Chen, Dayang Shi, Tingsheng Lu, Lihang Wang, Haoxi Li and Jianxun Wei
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:900
  24. The aim of this study was to analyse the efficacy of three-dimensional (3D)-printed screw guide-assisted percutaneous metatarsal transverse osteotomy (PMTO) for the treatment of mild-to-moderate hallux valgus ...

    Authors: Jiazheng Wang, Shaoling Fu, Cheng Wang, Shutao Zhang, Zhongmin Shi and Xin Ma
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:899
  25. This study aimed to examine pelvic morphology differences between adolescents with and without AIS, investigate variations among AIS patients with different scoliosis degrees and segments, and identify factors...

    Authors: Yi Shen, Feipeng Qin, Ndalyolusha Tileinge Hapulile, Yingsen Pan and Xiaoming Ying
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:898
  26. To evaluate the impact of long-term aspirin use (L-AU) on perioperative outcomes in Lumbar interbody fusion (LIF) using the US National Inpatient Sample (NIS) database.

    Authors: Hui Huang, Xuelian Wang and Qinfeng Yang
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:897
  27. To evaluate the biomechanical performance of a novel dual-cord and dual-spacer posterior dynamic stabilization system compared to a conventional single-threaded construct.

    Authors: Mehmet Yigit Akgun, Melihcan Savasci, Nazenin Durmus, Caner Gunerbuyuk, Tunc Oktenoglu, Ozkan Ates and Ali Fahir Ozer
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:895
  28. Osteonecrosis of the femoral head (ONFH) is a prevalent and refractory hip disease. In this study, we investigated the expression profiles of lipid metabolism-related genes in ONFH and evaluated the potential ...

    Authors: Yixiang He, Wanjia Qiao, Kui Zhang, Xuewen Shi and Wenji Wang
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:894
  29. Although percutaneous endoscopic lumbar discectomy (PELD) has become a classic operation for the treatment of lumbar disc herniation (LDH), its high recurrence rate remains a major problem that needs to be add...

    Authors: Si-ping Zhang, Min Tong, Jun Mo, Huan-wen Zhang, Zhen-yu Dong and Yi-fei Huang
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:893
  30. Osteochondral lesions of the talus (OLTs) involve damage to the articular cartilage and underlying bone, posing a therapeutic challenge due to the limited intrinsic healing capacity of cartilage. This review a...

    Authors: Jimmy Wen, Burhaan Syed, Ihab Abed, Mouhamad Shehabat, Muzammil Akhtar, Daniel Razick, Arsh Alam and Christopher Kreuelen
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:892
  31. Inertial measurement units (IMUs) offer a portable, affordable alternative to optical motion capture (OMC) systems for gait analysis. This systematic review and meta-analysis evaluated the concurrent validity ...

    Authors: Azamat Bissenov, Esra Zhubi, Marie Anne Engh, Orsolya Gresits, Réka Tóth and Tamás Terebessy
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:891
  32. Oblique lumbar interbody fusion (OLIF) and posterior lumbar interbody fusion (PLIF) are established techniques for the revision of adjacent segment disease (ASD) following prior lumbar fusion, yet the optimal ...

    Authors: Ming Chen, Xiaoyu Xia, Yifan Wei, Yu Jin, Cheng Ma, Yongxin Ren and You Lv
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:890
  33. Osteoporosis is a metabolic bone disease characterized by disruption of bone homeostasis, resulting from an imbalance between osteoblast-mediated bone formation and osteoclast-driven bone resorption. Emerging ...

    Authors: DuJiang Yang, GaoWen Gong, JiaFeng Song, JunJie Chen, Shuang Wang, Jingchi Li and GuoYou Wang
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:888
  34. This work focused on exploring the regulatory effect of long non-coding RNA (lncRNA)-ANRIL/miR-34a on rheumatoid arthritis (RA) fibroblasts (FLS), aiming to provide experimental support for clinical treatment ...

    Authors: Zhouzhou Xu, Chunhuai Wang and Long Qian
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:884
  35. This study evaluates the effects of exenatide (EXE), a glucagon-like peptide-1 (GLP-1) receptor agonist, on bone healing in rats using a single radius cortical defect model and histopathological, biochemical, ...

    Authors: Fatih Ugur, Ibrahim Yilmaz, Ersin Guner, Mehmet Albayrak, Recep Taskin, Nurtac Sarikas, Mehmet Akif Bildirici, Ayse Basak Dellalbasi and Candemir Ozcan
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:883
  36. Orthopaedic surgery remains one of the least gender-diverse medical specialties, with women making up a small fraction of practicing surgeons despite increasing female enrolment in medical schools. The “leaky ...

    Authors: Ahmad Furqan Anjum, Muhammad Burhan Anjum, Rahmeen Nauman and Raza ur Rehman Rana
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:881
  37. The transition in arthroscopic rotator cuff repair from single-row to double-row techniques has highlighted the efficacy of the suture-bridge configuration in providing enhanced biomechanical stability and cov...

    Authors: Songlin Liu and Liang Ma
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:879
  38. To investigate the factors influencing the healing of open fractures in circumpolar latitude region seawater immersion conditions.

    Authors: Shuo Sun, Hui Wang, Bin Han, Hongri Wu, Yangkai Wang and Tianming Xu
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:875
  39. Severe hallux valgus deformity with hallux valgus angle (HVA) greater than 40° presents significant challenges in surgical management. The metatarsal mid-shaft chevron osteotomy (MSCO) with spear plate fixatio...

    Authors: Kuan-Jung Chen, Chien-Yuan Wang, Chao-Ching Chiang, Chien-Shun Wang, Chien-Hua Chen and Tzu-Cheng Yang
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:874
  40. The management of femoral neck fractures (FNF) in elderly patients depends on comorbidities, pre-fracture mobility, any hip joint disease, and life expectancy, with treatment typically involving either hemiart...

    Authors: Clemens Roitzsch, Cecilia Rogmark, Yinan Wu, Alexander Grimberg, Jörg Lützner and Anne Postler
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:873
  41. Heterotopic ossifications (HO) are frequently observed after joint replacement surgery and may impair joint mobility and clinical outcomes. The incidence and clinical relevance of HO in revision reverse should...

    Authors: Raphael Trefzer, Michel Leisner, Mustafa Hariri, Johannes Weishorn, Paul Mick and Matthias Bülhoff
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:871
  42. Biodegradable implants have raised constant interest for fixation of displaced radial head fractures due to avoiding implant removal and minimizing cartilage damage. Polylactide pins (PP) are frequently used i...

    Authors: Julian P. Maier, Jonas Eck, Benjamin Erdle, Nils Mühlenfeld, Michael Seidenstuecker, Kilian Reising, Hagen Schmal and Ferdinand C. Wagner
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:870

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