The effect of herbal product interaction project

1-Asmaa Khaled Shehab 5114053
2-Alaa Gamal lallo 5114064
3-Alaa Hasan Hasan 5114065
4-Alaa mohamed Moussa 5114071
5-Afnan Maher Ali 5114059
6-Radwa Mohamed Abdelalim 5114157
7-Eslam Saad sobhy 5114046
8-Eslam Shalaby Khamis 5114047
PRESENTED BY

 Introduction About The Effect Of Herbal Product Interaction.
 Aim Of Investigation.
 Statistical analysis for results
 details and information about 6 herbal combination and 10
pharmaceutical products
Headlines:

 Because dietary supplements are becoming increasingly
popular, physicians need to ask questions about the use of
herbal products as part of the medication history. Even though
herbal products are available without a prescription, medical
guidance is necessary because of the adverse effects of these
products and the potential for interactions.
 Consequently, physicians need to stay abreast of trends in
dietary supplement use, with the realization that for most
supplements the adverse effects and potential for
interactions are not well characterized.
Introduction About The Effect Of Herbal
Product Interaction

 Gathering information about Herbs interaction from different
sites “Herbal supplier, Pharmacies, And audience
 Identifying some useful herbs combination and harmful herbal
combination”
 Knowing uses & Main constituents of this pharmaceutical
products and combination
 Understanding the interaction within pharmaceutical product
 Indication adverse effects interaction and side effects of this
products
 Knowing the patient compliance to herbal products
(combination ,herbal tea bags).
Aim Of Investigation

 Brand Name: linden Combination– ‫الزيزفرون‬ ‫وصفة‬
 Constituents: Guava leaves ,Tilia ,Anise , inden.
 Uses: treatment of wet cough and common cold.
 Side effects: there is no complains
 Comment: Interaction of this combination could cause
weakness in heart and allergy in skin. And it shouldn’t be use
in pregnancy and breast feeding. (They are antagonism)
Effect Of Some Herbal Combination From
Herbal Suppliers (Questionnaire 1-a)

 Brand Name: halva combination ‫وصفة‬‫الحلفا‬-
 Constituents: Ammi seeds, Parsley, Barley
 Uses: for kidney stones, salts and sedimentation of kidney,
and cure for colic.
 Side effects: dehydration – diuretics.
 Comment: should used in caution with kidney failure patient
as it may cause drought diuretics and dehydration
as the herbal supplier said used for stomachache.

 Brand Name: fat burning Combination– ‫للدهون‬ ‫الحارقة‬ ‫االعشاب‬
 Constituents: Marble , black cumin ,Mint, with other
ingredient.
 Uses: for weight loss
 Side effects: No side effect
 Comment: this combination could cause lowering in blood
pressure ,dizziness and a having a dangerous effect to
pregnant women.

 Brand Name: Tilia And thyme
 Constituents: Tilia And thyme
 Uses: headache & runny nose
 Side effects: No side effects has been recorded
 Comment: there were no interaction, this combination is a
synergism
Herbal Tea Bags Combination
(Questionnaire 1-b)

 Brand Name: Royal tea/ isis ginger and cinnamon
 Constituents: ginger and cinnamon
 Uses: for weight loss
 Side effects: diarrhea
 Comment: there were no interaction ,the combination is a
synergism

 Brand Name: ginger and cinnamon
 Constituents: ginger and cinnamon
 Uses: weight loss- enhance immunity-
 Side effects: may lead to increase gastric acidity
 Comment: after searching we found that this interaction may
lead to ulcer in stomach and gastritis, cinnamon my hurts the
spleen and ginger may increase the heart beats above normal,
and decrease sugar level in blood. Ginger and cinnamon may
affect nervous system (they are synergism).

 Trade Name: (Guava Syrup)
 Main Constituents: Aqueous extract of guava leaves, Tilia
Extract, fennel oil & Extract of liquorice root.
 Uses: Antitussive
 Side effects: large dose could cause diarrhea
 Comment:
 This product shouldn’t used by uncontrolled diabetes mellitus patient
 Shouldn’t be taken with ginger as Guava increase Blood glucose level
while ginger decrease blood glucose level
 Shouldn’t be taken with warfarin.
 Not to be used by pregnant women suffering from liver or renal
disease.
Herbal Products In Pharmacy
(Questionnaire 3)

 Trade Name: Immunavita oral drops
 Main Constituents:Extract of Echinacea purpurea volatile oil,
caffeine , ferulic acid derivatives
 Uses: dietary supplement improve function of immune system
 Side effects: No Recorded side effects
 Comment: it may interact with immunosuppressive therapy as
Athathioprine and Cyclosprine

 Trade Name: Mentholax
 Main Constituents: Pepperment oil & purified Senna Extract
 Uses: Laxative, carminative, antispasmodics
 Side effects: No Recorded side effects
 Comment: Senna increase toxicity of digitalis

Questionnaire-2 (Audience)
 Sample No: 10
 We collected surveys from Alexandria , Damanhur, somoha &
Dossq
 The females were more than males.
 People mainly age was 31-50.
 the majority of people trust in medical herbs in treatment of
some disease
 The majority have you used medical herbs in treatment of
some disease before.
 People mainly brought the medical herbs form Spice dealers
 Audience mainly prefer to use one herb alone rather than
group

 All the people has improvement happened after using medical
herbs.
 In the majority no side effects has appeared.
 Mainly people doesn’t stop using the herbs after the side
effect appearing
 Usually these signs hasn’t improved after stop using medical
herbs

 Comment:
We collected surveys from Alexandria , Damanhur, somoha
& Dossq
AREA
Area Alexandria Damanhour Somoha Dossq
50% 40% 10% 10%

Area
Alexandria
Damanhour
Somoha
Dossq

 Comment
The females were more than males.
GENDER
Gender Male female
20 80

0
10
20
30
40
50
60
70
80
90
Male female
Gender

 Comment
People mainly age was 31-50.
AGE
Age 15-30 31-50 51-75
30 40 30

0
5
10
15
20
25
30
35
40
45
15-30 31-50 51-75
Age

 Comment:
the majority of people trust in medical herbs in treatment
of some disease.
DO YOU TRUST IN USING MEDICAL HERBS
IN TREATMENT OF SOME DISEASE?
Do you trust in using
medical herbs in
treatment of some
disease?
Yes No
80 20

0
10
20
30
40
50
60
70
80
90
Yes No
Do you trust in using medical herbs in treatment of some disease?

 Comment
The majority have you used medical herbs in treatment of
some disease before.
HAVE YOU USED MEDICAL HERBS IN
TREATMENT OF SOME DISEASE BEFORE?
Have you used medical
herbs in treatment of some
disease before?
Yes No
90 10

0
10
20
30
40
50
60
70
80
90
100
Yes No
Have you used medical herbs in treatment of some disease before?

 Comment
People mainly brought the medical herbs form Spice
dealers
WHAT IS YOUR SOURCE TO GET
MEDICAL HERBS?
What is your source
to get medical
herbs?
Pharmacies spice dealer Company
40 60 0

0
10
20
30
40
50
60
70
Pharamcies spice dealer Company
What is your source to get medical herbs?

 Comment
Audience mainly prefer to use one herb alone rather than
group.
DO YOU PREFER TO USE ONE
HERB ALONE OR AS GROUP?
Do you prefer to use
one herb alone or as
group?
alone group
60 40

0
10
20
30
40
50
60
70
alone group
Do you prefer to use one herb alone or as group?

 Comment
All the people has improvement happened after using
medical herbs.
IS THERE IMPROVEMENT HAPPENED IN
MEDICAL SITUATION AFTER USING MEDICAL
HERBS?
Is there improvement happened in
medical situation after using medical
herbs?
yes no
100 0

0
20
40
60
80
100
120
yes no
Is there improvement happened in medical situation after using
medical herbs?

 Comment
In the majority no side effects has appeared.
IS THERE ANY SIDE EFFECTS APPEAR
AFTER USING MEDICAL HERBS?
Is there any side effects appear after using
medical herbs?
yes no
40 60

0
10
20
30
40
50
60
70
yes no
Is there any side effects appear after using medical herbs?

 Comment
Mainly people doesn’t stop using the herbs after the side
effect appearing
HAVE YOU STOPPED USING THE HERB
AFTER THE SIDE EFFECT APPEARING
?
Have you stopped using the herb
after the side effect appearing ?
yes no
40 60

0
10
20
30
40
50
60
70
yes no
Have you stopped using the herb after the side effect appearing ?

 Comment
Usually these signs hasn’t improved after stop using
medical herbs
DID THESE SIGNS IMPROVED AFTER
STOP USING MEDICINAL HERBS?
Did these signs improved after stop using
medicinal herbs?
yes no
40 60

0
10
20
30
40
50
60
70
yes no
Did these signs improved after stop using medicinal herbs?

 1-Nactional Center for complementary and alterative medicine
(NCCIH).
 2-Ghayur,M.N, Pharmacol. 2005
 http://herbs.lovetoknow.com/Side_Effects_of_Herbal_Medicin
e
Reference

The effect of herbal product interaction project

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