David de Boer gave a presentation on caching and invalidation with PHP and HTTP. He explained that caching can reduce response times and server load. The key challenges are cache invalidation and efficient caching through maximizing hits and infinite TTLs. He demonstrated using Varnish and Nginx caches with FOSHttpCache for purging, invalidating by regex, tags, and routes. Tests were also shown to validate invalidation. The FOSHttpCacheBundle integrates this with Symfony through annotations.