This document provides guidance for deploying NComputing L-series and vSpace software on virtual machines hosted on a VMware ESXi hypervisor. It discusses considerations for sizing the host server's processor, memory, storage, and network to support a given number of virtual desktop users. The document provides optimization tips for implementing virtual machines in ESXi and windows virtual machines. It aims to help users deploy NComputing solutions with server virtualization infrastructure in a scalable and manageable way.