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Basic Concepts Of Retrosynthesis (Part 2)
The document discusses retrosynthetic analysis approaches for synthesizing 1-phenylhexanol. It presents 6 different retrosynthetic disconnections and proposed syntheses, considering factors like availability of reagents and minimizing synthetic steps. The best synthesis is the one that uses readily available reagents and fewest steps, while breaking carbon-carbon bonds in the center of the molecule.
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Introduction to the retrosynthetic approach for organic synthesis presented by Dr. Shaikh S. Nizami.
An outline of the contents with examples, focusing on the analysis of 1-Phenylhexanol.
Detailed first analysis of 1-Phenylhexanol to showcase the retrosynthetic approach.
Introduction to the synthesis process involved in the retrosynthetic analysis.
Second retrosynthetic analysis of 1-Phenylhexanol continuing synthesis explanation.
Third retrosynthetic analysis of 1-Phenylhexanol with continued focus on synthesis.
Fourth retrosynthetic analysis of 1-Phenylhexanol, maintaining synthesis discussion.
Fifth retrosynthetic analysis of 1-Phenylhexanol emphasizing further synthesis details.
Final sixth retrosynthetic analysis of 1-Phenylhexanol, completing the synthesis series.
Important considerations for effective synthesis: reagent availability, steps minimization, and C-C bond disconnection.
A repeated humorous element 'Help Tim to get a nibble of the Birthday Cake' with no scientific content.
Basic Concepts Of Retrosynthesis (Part 2)
- 1. RETROSYNTHETIC APPROCH TO ORGANIC SYNTHESIS Dr. Shaikh S. Nizami Department of Chemistry University of Karachi
- 2. BASIC CONCEPTS(Part 2)
- 3. CONTENTS Examples ofRetrosynthetic analysis of: 1-Phenylhexanol (TM 1.1)
- 4. RETROSYNTHETIC ANALYSIS 1-PHENYLHEXANOL (TM 1.1)
- 5. 1 st RETROSYNTHETIC ANALYSIS 1-PHENYLHEXANOL
- 6.
- 7. 2 nd RETROSYNTHETIC ANALYSIS 1-PHENYLHEXANOL
- 8.
- 9. 3 rd RETROSYNTHETIC ANALYSIS 1-PHENYLHEXANOL
- 10.
- 11. 4 th RETROSYNTHETIC ANALYSI 1-PHENYLHEXANOL
- 12.
- 13. 5 th RETROSYNTHETIC ANALYSIS 1-PHENYLHEXANOL
- 14.
- 15. 6 th RETROSYNTHETIC ANALYSIS 1-PHENYLHEXANOL
- 16.
- 17. What is thebest synthesis ? Availability of the reagent Synthetic step should be kept minimum unless there is an advantage of FGI Disconnection of C-C bond should be in the center of a molecule
- 18. Help Tim toget a nibble of the Birthday Cake!
- 19. Help Tim geta nibble of the Birthday Cake!
- 20. Help Tim geta nibble of the Birthday Cake!
- 21. Help Tim geta nibble of the Birthday Cake!