Joseph Albert Nefario, most commonly referred to as Dr. Nefario (born August 12, 1928), is one of the two overarching protagonists (alongside Silas Ramsbottom) of the Despicable Me franchise. He is Gru's gadgeteer, residing in his underground lair and laboratories. He builds and designs most of Gru's machines. Gru and Dr. Nefario seem to have been trying to shock the world with "The True Crime of the Century" for several years. Although Dr. Nefario has doubts about Gru's plans due to lack...