Cell Death & Differentiation <p>Cell Death &amp; Differentiation is a journal devoted to the cell biology, molecular biology and biochemistry of cell death, survival, stemness and differentiation, both in normal tissue regulation and in disease. To this end, Cell death and Differentiation provides an accessible source of up-to-date information for scientists and clinicians. It is committed to the rapid publication of high-quality original papers that relate to these subjects, together with topical, usually solicited, reviews and meeting reports.</p><p/> http://feeds.nature.com/cdd/rss/current Nature Publishing Group en © 2025 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. Cell Death & Differentiation © 2025 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. [email protected]
  • Cell Death & Differentiation https://www.nature.com/uploads/product/cdd/rss.png http://feeds.nature.com/cdd/rss/current <![CDATA[CRISPR/Cas9 library screening uncovered CCT2 as a critical driver of acquired resistance to EGFR-targeted therapy by stabilizing TMX1 in non-small cell lung cancer]]> https://www.nature.com/articles/s41418-025-01600-w <![CDATA[
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    Cell Death & Differentiation, Published online: 30 October 2025; doi:10.1038/s41418-025-01600-w

    CRISPR/Cas9 library screening uncovered CCT2 as a critical driver of acquired resistance to EGFR-targeted therapy by stabilizing TMX1 in non-small cell lung cancer]]> <![CDATA[CRISPR/Cas9 library screening uncovered CCT2 as a critical driver of acquired resistance to EGFR-targeted therapy by stabilizing TMX1 in non-small cell lung cancer]]> Zihao KeQi ZhangXingyu ChenRongrong JinGaohua HanQianhua CaoKe ZhuShihui WeiJiajin ChenQian WangMeiling ZhangWeina HuangKaimin LiKunlong XiongKaihua LuYing ChenChao Cao doi:10.1038/s41418-025-01600-w Cell Death & Differentiation, Published online: 2025-10-30; | doi:10.1038/s41418-025-01600-w 2025-10-30 Cell Death & Differentiation 10.1038/s41418-025-01600-w https://www.nature.com/articles/s41418-025-01600-w <![CDATA[A STING for necroptosis]]> https://www.nature.com/articles/s41418-025-01602-8 <![CDATA[

    Cell Death & Differentiation, Published online: 28 October 2025; doi:10.1038/s41418-025-01602-8

    A STING for necroptosis]]>     <![CDATA[A STING for necroptosis]]> Marlena Nastassja SchlechtKarolin FladeWulf Tonnus doi:10.1038/s41418-025-01602-8 Cell Death & Differentiation, Published online: 2025-10-28; | doi:10.1038/s41418-025-01602-8 2025-10-28 Cell Death & Differentiation 10.1038/s41418-025-01602-8 https://www.nature.com/articles/s41418-025-01602-8     <![CDATA[Correction: USP20 positively regulates tumorigenesis and chemoresistance through β-catenin stabilization]]> https://www.nature.com/articles/s41418-025-01593-6 <![CDATA[

    Cell Death & Differentiation, Published online: 27 October 2025; doi:10.1038/s41418-025-01593-6

    Correction: USP20 positively regulates tumorigenesis and chemoresistance through β-catenin stabilization]]>     <![CDATA[Correction: USP20 positively regulates tumorigenesis and chemoresistance through β-catenin stabilization]]> Chenming WuKuntian LuoFei ZhaoPing YinYing SongMin DengJinzhou HuangYuping ChenLei LiSeungBaek LeeJungJin KimQin ZhouXinyi TuSomaira NowsheenQifeng LuoXiumei GaoZhenkun LouZhongmin LiuJian Yuan doi:10.1038/s41418-025-01593-6 Cell Death & Differentiation, Published online: 2025-10-27; | doi:10.1038/s41418-025-01593-6 2025-10-27 Cell Death & Differentiation 10.1038/s41418-025-01593-6 https://www.nature.com/articles/s41418-025-01593-6     <![CDATA[<i>circTGFBR2(3-6)</i> acts as an assembly platform for RNA-binding protein IGF2BP3 and <i>TGFBR1</i> mRNA to enhance breast cancer cell plasticity]]> https://www.nature.com/articles/s41418-025-01597-2 <![CDATA[

    Cell Death & Differentiation, Published online: 27 October 2025; doi:10.1038/s41418-025-01597-2

    circTGFBR2(3-6) acts as an assembly platform for RNA-binding protein IGF2BP3 and TGFBR1 mRNA to enhance breast cancer cell plasticity]]>     <![CDATA[<i>circTGFBR2(3-6)</i> acts as an assembly platform for RNA-binding protein IGF2BP3 and <i>TGFBR1</i> mRNA to enhance breast cancer cell plasticity]]> Qian WangRayman T. N. TjokrodirijoHailiang MeiPeter A. van VeelenPeter ten DijkeChuannan Fan doi:10.1038/s41418-025-01597-2 Cell Death & Differentiation, Published online: 2025-10-27; | doi:10.1038/s41418-025-01597-2 2025-10-27 Cell Death & Differentiation 10.1038/s41418-025-01597-2 https://www.nature.com/articles/s41418-025-01597-2     <![CDATA[Non-pyroptotic caspase-11 activity regulates osteoclastogenesis and pathological bone loss]]> https://www.nature.com/articles/s41418-025-01596-3 <![CDATA[

    Cell Death & Differentiation, Published online: 22 October 2025; doi:10.1038/s41418-025-01596-3

    Non-pyroptotic caspase-11 activity regulates osteoclastogenesis and pathological bone loss]]>     <![CDATA[Non-pyroptotic caspase-11 activity regulates osteoclastogenesis and pathological bone loss]]> Xianyu PiaoJu Han SongJung-Woo KimSeung-Hee KwonSin-Hye OhSangita SharmaSuk-Gyun ParkZhao WangZhiyu FangJe-Hwang RyuNacksung KimJeong-Tae Koh doi:10.1038/s41418-025-01596-3 Cell Death & Differentiation, Published online: 2025-10-22; | doi:10.1038/s41418-025-01596-3 2025-10-22 Cell Death & Differentiation 10.1038/s41418-025-01596-3 https://www.nature.com/articles/s41418-025-01596-3     <![CDATA[USP13 depletion sensitizes colorectal cancer cells to necroptosis by destabilizing cIAP2 proteins]]> https://www.nature.com/articles/s41418-025-01595-4 <![CDATA[

    Cell Death & Differentiation, Published online: 22 October 2025; doi:10.1038/s41418-025-01595-4

    USP13 depletion sensitizes colorectal cancer cells to necroptosis by destabilizing cIAP2 proteins]]>     <![CDATA[USP13 depletion sensitizes colorectal cancer cells to necroptosis by destabilizing cIAP2 proteins]]> Yeon Jung KimTanuza DasJinyoung ParkInah HwangEunice EunKyeong KimEun Joo Song doi:10.1038/s41418-025-01595-4 Cell Death & Differentiation, Published online: 2025-10-22; | doi:10.1038/s41418-025-01595-4 2025-10-22 Cell Death & Differentiation 10.1038/s41418-025-01595-4 https://www.nature.com/articles/s41418-025-01595-4     <![CDATA[Extrinsic apoptosis and necroptosis in telencephalic development: a single-cell mass cytometry study]]> https://www.nature.com/articles/s41418-025-01594-5 <![CDATA[

    Cell Death & Differentiation, Published online: 21 October 2025; doi:10.1038/s41418-025-01594-5

    Extrinsic apoptosis and necroptosis in telencephalic development: a single-cell mass cytometry study]]>     <![CDATA[Extrinsic apoptosis and necroptosis in telencephalic development: a single-cell mass cytometry study]]> Jiachen ShiWeile LiuAlison SongTimi SanniAmy Van DeusenEli R. ZunderChristopher D. Deppmann doi:10.1038/s41418-025-01594-5 Cell Death & Differentiation, Published online: 2025-10-21; | doi:10.1038/s41418-025-01594-5 2025-10-21 Cell Death & Differentiation 10.1038/s41418-025-01594-5 https://www.nature.com/articles/s41418-025-01594-5     <![CDATA[PDK4-driven lactate accumulation facilitates LPCAT2 lactylation to exacerbate sepsis-induced acute lung injury]]> https://www.nature.com/articles/s41418-025-01585-6 <![CDATA[

    Cell Death & Differentiation, Published online: 07 October 2025; doi:10.1038/s41418-025-01585-6

    PDK4-driven lactate accumulation facilitates LPCAT2 lactylation to exacerbate sepsis-induced acute lung injury]]>     <![CDATA[PDK4-driven lactate accumulation facilitates LPCAT2 lactylation to exacerbate sepsis-induced acute lung injury]]> Yifan DengYuetan QiuXiang LiTing GongJinyan GuoHaoxuan LiangZiyi YuanZiqing HeiXuedi ZhangYoutan Liu doi:10.1038/s41418-025-01585-6 Cell Death & Differentiation, Published online: 2025-10-07; | doi:10.1038/s41418-025-01585-6 2025-10-07 Cell Death & Differentiation 10.1038/s41418-025-01585-6 https://www.nature.com/articles/s41418-025-01585-6