Technical challenges and high costs remain barriers to the widespread application of microbial single-cell genomics. However, combining meta-omics approaches with single-cell genomics provides new opportunities to better understand microbial diversity, function and community dynamics.
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Engelberts, J.P., Tyson, G.W. Understanding microbial ecology and evolution with single-cell genomics. Nat Rev Genet 27, 3–4 (2026). https://doi.org/10.1038/s41576-025-00918-y
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DOI: https://doi.org/10.1038/s41576-025-00918-y
