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Going round in circles: the structural biology of type III secretion systems

Type III secretions systems (T3SSs) are major bacterial virulence factors responsible for secretion and injection of protein effectors into host cells. New structures illuminate their ring structure and identify novel ring-mediating structural scaffolds.

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Figure 1: Cryo-EM map of the S. flexneri

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Waksman, G. Going round in circles: the structural biology of type III secretion systems. Nat Struct Mol Biol 16, 459–460 (2009). https://doi.org/10.1038/nsmb0509-459

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