| Cell line name |
TS603 |
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| Accession |
CVCL_A5HW |
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| Resource Identification Initiative |
To cite this cell line use: TS603 (RRID:CVCL_A5HW) |
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| Comments |
Doubling time: ~7 days (Direct_author_submission).
Miscellaneous: STR profile and doubling time from MSKCC antibody and bioresource core facility.
Derived from site: In situ; Brain; UBERON=UBERON_0000955. |
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| Sequence variations |
|
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| Disease |
Anaplastic oligodendroglioma (NCIt: C4326)
Anaplastic oligodendroglioma (ORDO: Orphanet_251630) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Category |
Cancer cell line |
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| STR profile |
Source(s): Direct_author_submission
Markers:| Amelogenin | X |
| CSF1PO | 12 |
| D1S1656 | 11,15 |
| D2S441 | 10,11.3 |
| D2S1338 | 17,25 |
| D3S1358 | 16,18 |
| D5S818 | 11,13 |
| D7S820 | 10 |
| D8S1179 | 14,15 |
| D10S1248 | 13,16 |
| D12S391 | 20,22 |
| D13S317 | 8,9 |
| D16S539 | 12 |
| D18S51 | 14,16 |
| D19S433 | 15.2 |
| D21S11 | 29,32.2 |
| D22S1045 | 16 |
| FGA | 20,21 |
| Penta D | 8,14 |
| Penta E | 16 |
| TH01 | 7,9.3 |
| TPOX | 9,10 |
| vWA | 16,18 |
Run an STR similarity search on this cell line |
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| Web pages |
Provider; MSKCC; -; https://www.mskcc.org/research-advantage/support/technology/tangible-material/ts603-human-brain-cancer-glioblastoma-cell-line |
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| Publications |
PubMed=23558169; DOI=10.1126/science.1236062; PMCID=PMC3985613
Daniel Rohle, Janeta Popovici-Muller, Nicolaos Palaskas, Sevin Turcan, Christian Grommes, Carl Campos, Jennifer Tsoi, Owen Clark, Barbara Oldrini, Evangelia Komisopoulou, Kaiko Kunii ...Show all 28 authors... , Alicia Pedraza, Stefanie Schalm, Lee Silverman, Alexandra Miller, Fang Wang, Hua Yang, Yue Chen, Andrew Kernytsky, Marc K. Rosenblum, Wei Liu, Scott A. Biller, Shinsan M. Su, Cameron W. Brennan, Timothy A. Chan, Thomas G. Graeber, Katharine E. Yen, Ingo K. Mellinghoff; Show fewer authors
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells.
Science 340:626-630(2013) PubMed=33504762; DOI=10.1038/s41467-020-20752-6; PMCID=PMC7840755
Adrian Lita, Artem Pliss, Andrey N. Kuzmin, Tomohiro Yamasaki, Lu-Min Zhang, Tyrone Dowdy, Christina Burks, Natalia de Val, Orieta Celiku, Victor Ruiz-Rodado, Elena-Raluca Nicoli ...Show all 20 authors... , Michael J. Kruhlak, Thorkell Andresson, Sudipto Das, Chun-Zhang Yang, Rebecca Schmitt, Christel Herold-Mende, Mark R. Gilbert, Paras N. Prasad, Mioara Larion; Show fewer authors
IDH1 mutations induce organelle defects via dysregulated phospholipids.
Nat. Commun. 12:614.1-614.16(2021) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_A5HW
|
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| Encyclopedic resources |
Wikidata; Q107117130
|
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| Entry history |
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| Entry creation | 20-May-2021 |
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| Last entry update | 10-Apr-2025 |
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| Version number | 7 |
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