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Environmental Exposures and Lipid Homeostasis: Investigating the Impact of Pollutants on Metabolic Health

Edited by:

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Susanne Breitner-Busch, PhD, Helmholtz Munich, Germany
Kai Chen, PhD, Yale School of Public Health, United States of America

Submission Status: Closed

This collection is no longer accepting submissions.

Lipids in Health and Disease is calling for submissions to our new Collection on Environmental Exposures and Lipid Homeostasis: Investigating the Impact of Pollutants on Metabolic Health. This Collection focuses on the link between environmental factors and lipid homeostasis. 


New Content ItemThis Collection supports and amplifies research related to SDG 3: Good health and well-being.

  1. Evidence linking urinary metabolites of volatile organic compounds (UMVOCs) to dyslipidemia remains limited and scarce. This research sought to thoroughly clarify the UMVOCs-dyslipidemia associations and evalu...

    Authors: Lili Wu, Zhihang Ma, Yan Ma and Jing Gao
    Citation: Lipids in Health and Disease 2025 24:306
    Content type: Research Published on:

  2. Cadmium (Cd) is a heavy metal with nephrotoxicity. While the harmful effects of Cd exposure on the kidney have been extensively studied, the nephrotoxicity of Cd exposure on diabetic individual remain largely ...

    Authors: Changhao Li, Fuda Dong, Yilimilai Dilixiati, Yunbin Bai and Zengli Zhang
    Citation: Lipids in Health and Disease 2025 24:262
    Content type: Research Published on:

  3. Exposure of the lungs to particulate matter (i.e. dust, wildfire smoke, air pollution) places individuals at an increased risk for developing chronic respiratory disease. Recent work has demonstrated the effic...

    Authors: Logan S. Dean, Maëlis Wahl, Alissa N. Threatt, Morgan Pauly, Melea Barahona, Emmanuel O. Oyewole and Tara M. Nordgren
    Citation: Lipids in Health and Disease 2025 24:227
    Content type: Research Published on:

  4. Micro/nanoplastics (MNPs), as emerging environmental pollutants, are widely present in environments that are essential for human survival. They exist in vast quantities and possess stable properties, making th...

    Authors: Lijuan Chen, Guoyuan Sui, Jin Wu, Ning Li, Zhe Zhang, Ying Du, Meijun Lü, Xiaorui Yan, Guowei Pan and Lianqun Jia
    Citation: Lipids in Health and Disease 2025 24:195
    Content type: Research Published on:

  5. Maternal PM2.5 exposure and lipid levels during pregnancy were independently detected associated with birth weight. Potential mediating factors still remain unclear.

    Authors: Huiqi Chen, Qinqing Chen, Danxiao Wang, Min Lv, Liyun Wang, Yuan Chen, Fangfang Xi, Hefeng Huang and Qiong Luo
    Citation: Lipids in Health and Disease 2025 24:193
    Content type: Research Published on:

  6. The widespread presence of per-and polyfluoroalkyl substances (PFAS) has raised global health concerns. This study aims to determine the age-specific relationships of PFAS compounds with metabolic syndrome (Me...

    Authors: Luanxun Lin, Xiaoqin Lin, Shuaidan Chang, Yiqing Xing, Tao Zhou and Chunxue Yang
    Citation: Lipids in Health and Disease 2025 24:174
    Content type: Research Published on:

    The Correction to this article has been published in Lipids in Health and Disease 2025 24:314

  7. Exposure to brominated flame retardants (BFRs) has been linked to alterations in human metabolism and disease processes. However, the relationship between BFR exposure and blood lipid levels remains unclear. T...

    Authors: Yuxuan Wang, Zhihao Zhang, Nana Shen, Xiaoying Qi, Hao Li, Futong Wu, Zhongze Zhu, Jiarui Liu and Hongfei Xiang
    Citation: Lipids in Health and Disease 2025 24:120
    Content type: Research Published on:

  8. Ambient particulate matter (PM) exposure is recognized as a risk factor for cardiovascular disease (CVD). However, the extent to which PM exposure is associated with CVD via triglyceride glucose (TyG)-related ...

    Authors: Jiamin Xu, Tongle Yin, Mengshan Pan, Li Qin, Lu Zhang, Xiaoyan Wang, Weijun Zheng, Cuiqing Liu and Rucheng Chen
    Citation: Lipids in Health and Disease 2024 23:319
    Content type: Research Published on:

About the Collection

Lipid homeostasis involves maintaining a balance between lipid synthesis, storage, and utilization in the body. Coordination among various organs, including the liver, kidney, cardiovascular system, and adipose tissues, is needed. Dysregulation of lipid homeostasis has been shown to lead to the development of metabolic disorders, including obesity, diabetes, and cardiovascular disease, which are major health concerns worldwide.

Humans are exposed to various environmental pollutants, such as air pollutants, heavy metals, and persistent organic pollutants (POPs), as well as climate-related factors. Repeated and prolonged exposure to these factors may contribute to alterations in lipid homeostasis. However, how environmental exposures affect lipid homeostasis, including which groups are most vulnerable and the critical exposure windows is incompletely understood.

This Collection focuses on the link between environmental factors and lipid homeostasis. Understanding the role of these risk factors is essential for developing effective prevention strategies, especially those targeted at vulnerable population subgroups, and promoting policies aimed at limiting environmental release.

We welcome original research and (systematic) review articles, comments, and brief reports. Manuscripts on epidemiological, toxicological, and controlled human exposure studies will equally be accepted.

The collection may include, but is not limited to, the following topics:

• Associations between environmental factors (climate-related hazards or pollutants) and changes in clinical lipid markers
• Associations between environmental factors and changes in lipid metabolites or other associated metabolites and corresponding molecular, cellular, and systemic mechanisms
• Novel approaches to examine the exposome (internal or external) framework and multipollutant mixtures and their impact on lipid homeostasis.

Keywords: Environmental exposures, lipid homeostasis, metabolic diseases, pollutants, toxins, therapeutic strategies

Submission Guidelines

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This Collection welcomes submissions of original research and review articles, comments, and brief reports. Should you wish to submit a different article type, please read our submission guidelines to confirm that type is accepted by the journal. 

Articles for this Collection should be submitted via our submission system, Snapp. Please, select the appropriate Collection title “Environmental Exposures and Lipid Homeostasis: Investigating the Impact of Pollutants on Metabolic Health" under the “Details” tab during the submission stage.

Articles will undergo the journal’s standard peer-review process and are subject to all the journal’s standard policies. Articles will be added to the Collection as they are published.

The Editors have no competing interests with the submissions which they handle through the peer-review process. The peer-review of any submissions for which the Editors have competing interests is handled by another Editorial Board Member who has no competing interests.