National Health Research Institutes (NHRI)

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National Health Research Institutes (NHRI)'s Articles

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Induction of LY6E regulates interleukin-1β production, potentially contributing to the immunopathogenesis of systemic lupus erythematosus

Authors: Jenn-Haung Lai, De-Wei Wu, Chuan-Yueh Huang, Li-Feng Hung, Chien-Hsiang Wu, Shuk-Man Ka, Ann Chen, Jing-Long Huang and Ling-Jun Ho

Citation: Cell Communication and Signaling 2025 23:146

Content type: Research Published on: 20 March 2025
Survival of advanced/recurrent gastrointestinal stromal tumors treated with tyrosine kinase inhibitors in Taiwan: a nationwide registry study

Authors: Hui-Jen Tsai, Yan-Shen Shan, Ching-Yao Yang, Chin-Fu Hsiao, Chung-Hsin Tsai, Chuan-Cheng Wang, Ming-Tsan Lin, Chun-Fu Ting, De-Chuan Chan, Te-Hung Chen, Chueh-Chuan Yen, Yen-Yang Chen, Hsuan-Yu Lin, Ta-Sen Yeh, Ching-Liang Ho, Tze-Yu Shieh…

Citation: BMC Cancer 2024 24:828

Content type: Research Published on: 11 July 2024
Tumor promoting effect of PDLIM2 downregulation involves mitochondrial ROS, oncometabolite accumulations and HIF-1α activation

Authors: Jing-Xing Yang, Yu-Chen Chuang, Jen-Chih Tseng, Yi-Ling Liu, Chao-Yang Lai, Alan Yueh-Luen Lee, Chi-Ying F. Huang, Yi-Ren Hong and Tsung-Hsien Chuang

Citation: Journal of Experimental & Clinical Cancer Research 2024 43:169

Content type: Research Published on: 17 June 2024
Correction: Excess glucose alone depress young mesenchymal stromal/stem cell osteogenesis and mitochondria activity within hours/days via NAD⁺/ SIRT1 axis

Authors: B. Linju Yen, Li‑Tzu Wang, Hsiu‑Huang Wang, Chin‑Pao Hung, Pei‑Ju Hsu, Chia‑Chi Chang, Chien‑Yu Liao, Huey‑Kang Sytwu and Men‑Luh Yen

Citation: Journal of Biomedical Science 2024 31:61

Content type: Correction Published on: 7 June 2024

The original article was published in Journal of Biomedical Science 2024 31:49
Excess glucose alone depress young mesenchymal stromal/stem cell osteogenesis and mitochondria activity within hours/days via NAD⁺/SIRT1 axis

Authors: B. Linju Yen, Li-Tzu Wang, Hsiu-Huang Wang, Chin-Pao Hung, Pei-Ju Hsu, Chia-Chi Chang, Chien-Yu Liao, Huey-Kang Sytwu and Men-Luh Yen

Citation: Journal of Biomedical Science 2024 31:49

Content type: Research Published on: 13 May 2024

The Correction to this article has been published in Journal of Biomedical Science 2024 31:61
Increased di-(2-ethylhexyl) phthalate exposure poses a differential risk for adult asthma clusters

Authors: Yuan-Ting Hsu, Chao-Chien Wu, Chin-Chou Wang, Chau-Chyun Sheu, Yi-Hsin Yang, Ming-Yen Cheng, Ruay-Sheng Lai, Sum-Yee Leung, Chi-Cheng Lin, Yu-Feng Wei, Yung-Fa Lai, Meng-Hsuan Cheng, Huang-Chi Chen, Chih-Jen Yang, Chien-Jen Wang, Huei-Ju Liu…

Citation: Respiratory Research 2024 25:139

Content type: Research Published on: 23 March 2024
Germline mutations of homologous recombination genes and clinical outcomes in pancreatic cancer: a multicenter study in Taiwan

Authors: Siao Muk Cheng, Yung-Yeh Su, Nai-Jung Chiang, Chih-Jung Wang, Ying-Jui Chao, Chien-Jui Huang, Hui-Jen Tsai, Shang-Hung Chen, Chi-Yen Chang, Chia-Rung Tsai, Yi-Jie Li, Chia-Jui Yen, Shih-Chang Chuang, Jeffrey Shu-Ming Chang, Yan-Shen Shan, Daw-Yang Hwang…

Citation: Journal of Biomedical Science 2024 31:21

Content type: Research Published on: 13 February 2024
Dengue virus serotype did not contribute to clinical severity or mortality in Taiwan’s largest dengue outbreak in 2015

Authors: Jih-Jin Tsai, Ko Chang, Chun-Hong Chen, Ching-Len Liao, Liang-Jen Chen, Yan-Yi Tsai, Ching-Yi Tsai, Ping-Chang Lin, Miao-Chen Hsu and Li-Teh Liu

Citation: European Journal of Medical Research 2023 28:482

Content type: Research Published on: 6 November 2023
Correction: Periostin promotes ovarian cancer metastasis by enhancing M2 macrophages and cancer-associated fibroblasts via integrin-mediated NF-κB and TGF-β2 signaling

Authors: Sheng-Chieh Lin, Yi-Chu Liao, Po-Ming Chen, Ya-Yu Yang, Yi-Hsiang Wang, Shiao-Lin Tung, Chi-Mu Chuang, Yu-Wen Sung, Te-Hsuan Jang, Shuang-En Chuang and Lu-Hai Wang

Citation: Journal of Biomedical Science 2023 30:54

Content type: Correction Published on: 12 July 2023

The original article was published in Journal of Biomedical Science 2022 29:109
Krüppel-like factor 10 modulates stem cell phenotypes of pancreatic adenocarcinoma by transcriptionally regulating notch receptors

Authors: Yi-Chih Tsai, Kung Hung Cheng, Shih Sheng Jiang, John R. Hawse, Shun En Chuang, Su Liang Chen, Tze-Sing Huang and Hui-Ju Ch’ang

Citation: Journal of Biomedical Science 2023 30:39

Content type: Research Published on: 12 June 2023
Trends in energy and macronutrient intake among Taiwanese older adults in 1999–2000, 2005–2008 and 2013–2016 periods

Authors: Chih-Hsueh Lin, Hsing-Yi Chang, Tsai-Chung Li, Chiu-Shong Liu, Wen-Yuan Lin, Meng-Chih Lee, Li-Na Liao, Chia-Ing Li, Chih-Yi Hsiao, Hsin-Ling Fang, Wen-Tzu Wu and Cheng-Chieh Lin

Citation: BMC Public Health 2023 23:871

Content type: Research Published on: 12 May 2023
Periostin promotes ovarian cancer metastasis by enhancing M2 macrophages and cancer-associated fibroblasts via integrin-mediated NF-κB and TGF-β2 signaling

Authors: Sheng-Chieh Lin, Yi-Chu Liao, Po-Ming Chen, Ya-Yu Yang, Yi-Hsiang Wang, Shiao-Lin Tung, Chi-Mu Chuang, Yu-Wen Sung, Te-Hsuan Jang, Shuang-En Chuang and Lu-Hai Wang

Citation: Journal of Biomedical Science 2022 29:109

Content type: Research Published on: 22 December 2022

The Correction to this article has been published in Journal of Biomedical Science 2023 30:54
Cancer-derived extracellular succinate: a driver of cancer metastasis

Authors: Cheng-Chin Kuo, Jing-Yiing Wu and Kenneth K. Wu

Citation: Journal of Biomedical Science 2022 29:93

Content type: Review Published on: 7 November 2022
PTEN regulates invasiveness in pancreatic neuroendocrine tumors through DUSP19-mediated VEGFR3 dephosphorylation

Authors: Tsung-Ming Chang, Pei-Yi Chu, Hui-You Lin, Kuo-Wei Huang, Wen-Chun Hung, Yan-Shen Shan, Li-Tzong Chen and Hui-Jen Tsai

Citation: Journal of Biomedical Science 2022 29:92

Content type: Research Published on: 6 November 2022
Association of advanced paternal age with lung function at school age

Authors: Chun-Chun Gau, Hsin-Ju Lee, Hung-Yi Lu, Chao-Yi Wu, Hsin-Yi Huang, Hui-Ju Tsai and Tsung-Chieh Yao

Citation: Respiratory Research 2022 23:259

Content type: Research Published on: 20 September 2022
AKT phosphorylation as a predictive biomarker for PI3K/mTOR dual inhibition-induced proteolytic cleavage of mTOR companion proteins in small cell lung cancer

Authors: Ming-Chun Hung, Wan-Ping Wang and Ya-Hui Chi

Citation: Cell & Bioscience 2022 12:122

Content type: Research Published on: 2 August 2022
Aryl hydrocarbon receptor activation-mediated vascular toxicity of ambient fine particulate matter: contribution of polycyclic aromatic hydrocarbons and osteopontin as a biomarker

Authors: Chia-Chi Ho, Wei-Te Wu, Yi-Jun Lin, Chen-Yi Weng, Ming-Hsien Tsai, Hui-Ti Tsai, Yu-Cheng Chen, Shaw-Fang Yet and Pinpin Lin

Citation: Particle and Fibre Toxicology 2022 19:43

Content type: Research Published on: 23 June 2022
MicroRNA-485-5p targets keratin 17 to regulate oral cancer stemness and chemoresistance via the integrin/FAK/Src/ERK/β-catenin pathway

Authors: Te-Hsuan Jang, Wei-Chieh Huang, Shiao-Lin Tung, Sheng-Chieh Lin, Po-Ming Chen, Chun-Yu Cho, Ya-Yu Yang, Tzu-Chen Yen, Guo-Hsuen Lo, Shuang-En Chuang and Lu-Hai Wang

Citation: Journal of Biomedical Science 2022 29:42

Content type: Research Published on: 15 June 2022
Induction of high affinity monoclonal antibodies against SARS-CoV-2 variant infection using a DNA prime-protein boost strategy

Authors: Chen-Yi Chiang, Mei-Yu Chen, Chia-Wei Hsu, Chia-Yeh Liu, Yu-Wen Tsai, Hung-Chun Liao, Jia-Ying Yan, Zih-Shiuan Chuang, Hsin-I. Wang, Chien-Hsiung Pan, Chia-Yi Yu, Guann-Yi Yu, Ching-Len Liao, Shih-Jen Liu and Hsin-Wei Chen

Citation: Journal of Biomedical Science 2022 29:37

Content type: Research Published on: 9 June 2022
A new scoring system facilitating diagnosis of oral squamous malignancy on biopsy specimens

Authors: Cheng-Lin Wu, Cheng-Chih Huang, Shang-Yin Wu, Shih-Sheng Jiang, Fang-Yu Tsai and Jenn-Ren Hsiao

Citation: BMC Oral Health 2022 22:165

Content type: Research article Published on: 6 May 2022