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Systemic chemotherapy in metastatic TNBC polarizes effector T cell differentiation

Authors: Hye-Yeon Ju, Hyundong Yoon, Seungpil Jung, Serk In Park, Tae Kon Kim and Mi-Ryung Han

Citation: Cancer Cell International 2025 25:371

Content type: Research Published on: 22 October 2025
A standard-based taxonomy of features that affect user response to clinical decision support alerts

Authors: Siru Liu, Allison B. McCoy, Dean F. Sittig, Josh F. Peterson, Thomas A. Lasko and Adam Wright

Citation: BMC Medical Informatics and Decision Making 2025 25:389

Content type: Research Published on: 21 October 2025
Study protocol for the design, implementation, and evaluation of the STRATIFY clinical decision support tool for emergency department disposition of patients with heart failure

Authors: Sunil Kripalani, Deonni P. Stolldorf, Anna L. Sachs, Jennifer B. Barrett, Shilo H. Anders, Laurie L. Novak, Dandan Liu, Joseph Miller, Bory Kea, Isaac Schlotterbeck and Alan B. Storrow

Citation: Implementation Science Communications 2025 6:107

Content type: Study protocol Published on: 17 October 2025
The I-ACTED study (investigating action civics training through an experimental design): a cluster randomized controlled trial of a school-based action civics education intervention on adolescent wellbeing

Authors: Alison K. Cohen, Jason C. Fitzgerald, Grisel Trejo, Isabella U. Yalif, Paul D. Wesson, Mark Wolfson and Parissa J. Ballard

Citation: BMC Public Health 2025 25:3513

Content type: Study Protocol Published on: 16 October 2025
Feasibility of machine learning analysis for the identification of patients with possible primary ciliary dyskinesia

Authors: Gully Burns, Carey Kauffman, Michele Manion, Ruth-Anne Pai, Carlos Milla, Michael G. O’Connor, Adam J. Shapiro and Heidi Bjornson-Pennell

Citation: Orphanet Journal of Rare Diseases 2025 20:516

Content type: Research Published on: 14 October 2025
Hospital readmission disparity measure for evaluating hospital performance and penalties

Authors: Yajun Yi, Henry John Domenico, Leta Yi, Wei Xiang and Xiayu Xiang

Citation: Archives of Public Health 2025 83:241

Content type: Research Published on: 11 October 2025
Potential therapeutic benefit of exogenous ketone ester administration in delirium: a narrative review

Authors: Ryan Smith, Fiona Harrison, Julie Bastarache, Shawniqua Williams Roberson, Elma Zaganjor, Pratik Pandharipande, Todd Rice and Wes Ely

Citation: Critical Care 2025 29:424

Content type: Review Published on: 7 October 2025
TrueSpot: a robust automated tool for quantifying signal puncta in fluorescent imaging

Authors: Blythe G. Hospelhorn, Benjamin K. Kesler, Hossein Jashnsaz and Gregor Neuert

Citation: Genome Biology 2025 26:317

Content type: Software Published on: 29 September 2025
The development of the sustainability measure for healthcare using a modified Delphi process

Authors: Deonni P. Stolldorf, Abigail C. Jones and Mary S. Dietrich

Citation: BMC Health Services Research 2025 25:1215

Content type: Research Published on: 26 September 2025
Cache: Utilizing ultra-large library screening in Rosetta to identify novel binders of the WD-repeat domain of Leucine-Rich Repeat Kinase 2

Authors: Fabian Liessmann, Paul Eisenhuth, Alexander Fürll, Oanh Vu, Rocco Moretti and Jens Meiler

Citation: Journal of Cheminformatics 2025 17:145

Content type: Research Published on: 25 September 2025
Community-based participatory research to guide adoption of culturally responsive trauma-informed HIV care throughout Nashville, Tennessee

Authors: L. Lauren Brown, Jessica M. Perkins, A. Jessica Acuña, Julie Thacker, Clare Bolds, Mary Hawkins, Jamie L. Stewart, Julie Barroso, Sadie B. Sommer, Joshua Van der Eerden, Bryan W. Heckman, Amna Osman, Tarik Smith, LaToya Alexander, Allie Denton, Tiye Link…

Citation: BMC Health Services Research 2025 25:1127

Content type: Research Published on: 25 August 2025
The role of skin testing, drug challenge and IFN-γ ELISpot in delayed hypersensitivity to iodinated contrast media

Authors: Ana Maria Copaescu, Kyra Y. L. Chua, Effie Mouhtouris, Natasha E. Holmes, Moneerah AlGassim, Ibtihal Al Otaibi, Florian Stehlin, Ghislaine A. C. Isabwe, Christos Tsoukas, Jean-Francois Toupin, Derek Lee, Moshe Ben-Shoshan, Elizabeth J. Phillips and Jason A. Trubiano

Citation: Allergy, Asthma & Clinical Immunology 2025 21:35

Content type: Research Published on: 14 August 2025
LRRK2 kinase activity regulates Parkinson’s disease-relevant lipids at the lysosome

Authors: Michael T. Maloney, Xiang Wang, Rajarshi Ghosh, Shan V. Andrews, Romeo Maciuca, Shababa T. Masoud, Maayan Agam, Richard M. Caprioli, Giuseppe Astarita, Vitaliy V. Bondar, John Chen, Chi-Lu Chiu, Sonnet S. Davis, Audrey Cheuk-Nga Ho, Hoang N. Nguyen, Nicholas E. Propson…

Citation: Molecular Neurodegeneration 2025 20:89

Content type: Research article Published on: 6 August 2025
Shared decision-making for pediatric acute otitis media in the United States: a randomized emergency department trial

Authors: Jana L. Anderson, Lucas Oliveira J. E. Silva, Erik P. Hess, Derek E. Vanmeter, Aidan Mullan, Juan P. Brito, Ian G. Hargraves and Fernanda Bellolio

Citation: BMC Emergency Medicine 2025 25:146

Content type: Research Published on: 2 August 2025
Optimizing treatment for depression in primary care using psychotherapy versus antidepressant medication in a low-resource setting: protocol for the OptimizeD randomized controlled trial

Authors: Julia R. Pozuelo, Anuja Lahiri, Rahul S. P. Singh, Arvind Kushwah, Mimansa Khanduri, Akanksha Shukla, Azaz Khan, Sruthi G., Varun Shende, Yashika Parashar, Yashwant K. Mehra, Anant Bhan, Ronald C. Kessler, Daisy R. Singla, John A. Naslund, Karmel W. Choi…

Citation: BMC Psychiatry 2025 25:744

Content type: Study Protocol Published on: 30 July 2025
SuperMetal: a generative AI framework for rapid and precise metal ion location prediction in proteins

Authors: Xiaobo Lin, Zhaoqian Su, Yunchao Lance Liu, Jingxian Liu, Xiaohan Kuang, Peter T. Cummings, Jesse Spencer-Smith and Jens Meiler

Citation: Journal of Cheminformatics 2025 17:107

Content type: Research Published on: 15 July 2025
Substrate stiffness and shear stress collectively regulate the inflammatory phenotype in cultured human brain microvascular endothelial cells

Authors: Alexis K. Yates, Heather Murray, Andrew Kjar, Daniel Chavarria, Haley Masters, Hyosung Kim, Alexander P. Ligocki, Angela L. Jefferson and Ethan S. Lippmann

Citation: Fluids and Barriers of the CNS 2025 22:73

Content type: Research Published on: 15 July 2025
Association between serial changes in serum C-reactive protein levels and mortality among patients with pleural empyema: a database research

Authors: Akihiro Shiroshita, Masafumi Takeshita, Teruaki Nishiuma, Tomoaki Ota and Yuki Kataoka

Citation: BMC Pulmonary Medicine 2025 25:337

Content type: Research Published on: 12 July 2025
Individualizing pediatric boarding care: child perspectives

Authors: Emily D. Irwin, Briana P. Keller, Andrea Hughie, Patti Runyan and Jessika C. Boles

Citation: BMC Pediatrics 2025 25:499

Content type: Research Published on: 2 July 2025
X-ray velocimetry provides temporally and spatially-resolved biomarkers of lung ventilation in small airways disease

Authors: Bradley W. Richmond, Michael G. Lester, Vincent Lui, Jonathan Dusting, Sarath Raju, Gregory I. Snell, Jessica B. Blackburn, Katrina Douglas, Robert F. Miller, Trishul Siddharthan and Andreas Fouras

Citation: Respiratory Research 2025 26:226

Content type: Research Published on: 2 July 2025