Prospects for adoptive T cell therapy
- PMID: 9368780
- DOI: 10.1016/s0952-7915(97)80052-0
Prospects for adoptive T cell therapy
Abstract
Since the establishment of methods to isolate genes encoding cytotoxic T lymphocyte defined tumor antigens, several antigens have been identified and characterized for suitability as target antigens for immunotherapy. The development of innovative strategies to generate T cells targeting these antigens and lessons learned from clinical trials of adoptive immunotherapy of viral diseases should facilitate the design of clinical trials for specific adoptive immunotherapy of cancer.
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