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. 1984;307(5949):334-40.
doi: 10.1038/307334a0.

Activation of a translocated human c-myc gene by an enhancer in the immunoglobulin heavy-chain locus

A C Hayday, S D Gillies, H Saito, C Wood, K Wiman, W S Hayward, S Tonegawa

Activation of a translocated human c-myc gene by an enhancer in the immunoglobulin heavy-chain locus

A C Hayday et al. Nature. 1984.

Abstract

A tissue-specific transcriptional enhancer element that is associated with the human immunoglobulin heavy-chain locus is defined. In a non-Hodgkin's lymphoma that contains a translocated c-myc gene this enhancer is retained on the 14q+ chromosome and occurs within sequences shown to activate previously cryptic promoters of the c-myc gene.

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