Integrated stress response mediates cognitive decline in Down syndrome
- PMID: 31802033
- DOI: 10.1038/s41582-019-0298-6
Integrated stress response mediates cognitive decline in Down syndrome
Comment on
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Activation of the ISR mediates the behavioral and neurophysiological abnormalities in Down syndrome.Science. 2019 Nov 15;366(6467):843-849. doi: 10.1126/science.aaw5185. Science. 2019. PMID: 31727829 Free PMC article.
References
Original article
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- Zhu, P. J. et al. Activation of the ISR mediates the behavioral and neurophysiological abnormalities in Down syndrome. Science 366, 843–849 (2019) - DOI
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- Lott, I. T. & Head, E. Dementia in Down syndrome: unique insights for Alzheimer disease research. Nat. Rev. Neurol. 15, 135–147 (2019) - DOI
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