Skip to main page content
U.S. flag
See More

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Mar;18(2):103-15.
doi: 10.3109/1354750X.2012.749302. Epub 2013 Jan 23.

Clinical and research markers of oxidative stress in chronic kidney disease

Patrick Steven Tucker  1 , Vincent James Dalbo, Thin Han, Michael Ian Kingsley
Affiliations

Clinical and research markers of oxidative stress in chronic kidney disease

Patrick Steven Tucker et al. Biomarkers. 2013 Mar.

Abstract

Context: Kidney-related pathologies have increasing prevalence rates, produce a considerable financial burden, and are characterized by elevated levels of oxidative stress (OS).

Objective: This review examines relationships between chronic kidney disease (CKD) and markers of OS and antioxidant status (AS).

Methods: A systematic review of MEDLINE-indexed clinical trials, randomized controlled trials and comparative studies that examined OS and AS was performed.

Results and conclusion: Several markers emerged as well-suited indicators of OS and AS in CKD: malondialdehyde, F2-isoprostanes, lipid hydroperoxides, asymmetric dimethylarginine, 8-oxo-7,8-dihydro-2'-deoxyguanosine, protein carbonyls, advanced oxidation protein products and glutathione-related activity.

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources