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. 2009 Jul;37(Web Server issue):W296-9.
doi: 10.1093/nar/gkp268. Epub 2009 Apr 30.

The Microbe browser for comparative genomics

Affiliations

The Microbe browser for comparative genomics

Alexandre Gattiker et al. Nucleic Acids Res. 2009 Jul.

Abstract

The Microbe browser is a web server providing comparative microbial genomics data. It offers comprehensive, integrated data from GenBank, RefSeq, UniProt, InterPro, Gene Ontology and the Orthologs Matrix Project (OMA) database, displayed along with gene predictions from five software packages. The Microbe browser is daily updated from the source databases and includes all completely sequenced bacterial and archaeal genomes. The data are displayed in an easy-to-use, interactive website based on Ensembl software. The Microbe browser is available at http://microbe.vital-it.ch/. Programmatic access is available through the OMA application programming interface (API) at http://microbe.vital-it.ch/api.

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Figures

Figure 1.
Figure 1.
Chromosome view of Mycobacterium tuberculosis CDC 1551. GenBank source annotation (black full boxes), Genome Reviews reference annotation from UniProtKB (coloured full boxes) and predictions from five software packages (hollow boxes). UniProtKB curators have altered the most likely translational start site of the MT1457 gene by similarity to other genomes and created a novel conserved gene identical to M. tuberculosis H37Rv gene Rv1413.
Figure 2.
Figure 2.
Chromosome comparison view of regions around the pgl gene in Escherichia coli O157:H7, E. coli K12 and Yersinia pestis KIM5. Genes are coloured by InterPro families, and orthologous gene pairs are connected. Among the adjacent mod, ybh and bio genes present in E. coli K12, only two are conserved in synteny in each species.

References

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