Epicardial control of myocardial proliferation and morphogenesis
- PMID: 19277768
- DOI: 10.1007/s00246-009-9391-8
Epicardial control of myocardial proliferation and morphogenesis
Abstract
The epicardium is a critical tissue that directs several aspects of heart development, particularly via the secretion of soluble factors. This review summarizes recent approaches that implicate the epicardium as the source of mitogenic factors promoting cardiomyocyte proliferation, as the source of instructive signals that direct compact zone organization (morphogenesis), and as the tissue that directs formation of the coronary vasculature.
References
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
