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Review
. 1991 Dec;16(12):478-81.
doi: 10.1016/0968-0004(91)90184-w.

Nuclear targeting sequences--a consensus?

C Dingwall  1 , R A Laskey
Affiliations
Review

Nuclear targeting sequences--a consensus?

C Dingwall et al. Trends Biochem Sci. 1991 Dec.

Abstract

Nuclear targeting sequences are essential for the transport of proteins into the nucleus. The seven-amino-acid nuclear targeting sequence of the SV40 large T antigen has been regarded as the model; however, many nuclear targeting sequences appear to be more complex. We suggest in this review that, despite this diversity, a consensus bipartite motif can be identified.

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