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Review
. 2006 Feb 24;124(4):715-27.
doi: 10.1016/j.cell.2006.02.012.

Bacterial adhesion and entry into host cells

Javier Pizarro-Cerdá  1 , Pascale Cossart
Affiliations
Free article
Review

Bacterial adhesion and entry into host cells

Javier Pizarro-Cerdá et al. Cell. .
Free article

Abstract

Successful establishment of infection by bacterial pathogens requires adhesion to host cells, colonization of tissues, and in certain cases, cellular invasion-followed by intracellular multiplication, dissemination to other tissues, or persistence. Bacteria use monomeric adhesins/invasins or highly sophisticated macromolecular machines such as type III secretion systems and retractile type IV pili to establish a complex host/pathogen molecular crosstalk that leads to subversion of cellular functions and establishment of disease.

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