Skip to main page content
U.S. flag
See More

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2001 Dec 28;107(7):827-30.
doi: 10.1016/s0092-8674(01)00623-7.

The unfolding tale of the unfolded protein response

Y Ma  1 , L M Hendershot
Affiliations
Free article
Review

The unfolding tale of the unfolded protein response

Y Ma et al. Cell. .
Free article

Abstract

Surface and secreted proteins are synthesized in the endoplasmic reticulum where they must fold and assemble before being transported. Changes in the ER that interfere with their proper maturation initiate the unfolded protein response pathway. New studies have filled in a missing link between the yeast and mammalian pathways.

PubMed Disclaimer

Substances

LinkOut - more resources