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Table 4 Linear regression analysis for correlates of serum non-HDL-c levels among people with HIV

From: Cotrimoxazole use is associated with lower total and non-high density lipoprotein cholesterol among people with HIV: a cross-sectional study

Characteristic

Crude β coefficient

95% CI

P-value

Adjusted β

95% CI

P-value

Currently on cotrimoxazole prophylaxis

 No

Ref

  

Ref

  

 Yes

−0.53

(−0.77, −0.30)

< 0.001

−0.34

(−0.58, −0.11)

0.005

Sex

 Male

Ref

  

Ref

  

 Female

0.23

(0.02, 0.43)

0.034

0.16

(−0.13, 0.44)

0.289

TB History

 No

Ref

  

Ref

  

 Yes

−0.39

(−0.60, −0.19)

< 0.001

−0.16

(−0.72, 0.39)

0.556

Current Opportunistic Infection

 No

Ref

  

Ref

  

 Yes

−0.52

(−0.97, −0.07)

0.023

−0.09

(−0.53, 0.35)

0.676

Alcohol Use

 Never used alcohol

Ref

  

Ref

  

 Formerly used alcohol (> 6 months)

0.07

(−0.18, 0.33)

0.561

0.11

(−0.13, 0.36)

0.370

 Currently uses alcohol (< 6 months)

−0.31

(−0.55, −0.06)

0.017

−0.26

(−0.54, 0.01)

0.059

Smoking

 Never smoked

Ref

  

Ref

  

 Formerly smoked (> 6 months)

−0.19

(−0.51, 0.12)

0.225

−0.09

(−0.41, 0.23)

0.573

 Currently smokes (< 6 months)

−0.57

(−0.98, −0.15)

0.007

−0.26

(−0.67, 0.15)

0.215

Conjunctival Pallor

 No

Ref

  

Ref

  

 Yes

−0.42

(−0.73, −0.12)

0.006

−0.39

(−0.69, −0.08)

0.013

Abnormal Chest Exam

 No

Ref

  

Ref

  

 Yes

−0.64

(−1.01, −0.26)

0.001

−0.56

(−0.94, −0.19)

0.003

Hypertension

 No

Ref

  

Ref

  

 Yes

0.23

(0.01, 0.45)

0.045

−0.11

(−0.34, 0.13)

0.373

Central Obesity

 No

Ref

  

Ref

  

 Yes

0.45

(0.24, 0.65)

< 0.001

0.15

(−0.13, 0.42)

0.304

Past LRTI

 No

Ref

  

Ref

  

 Yes

−0.39

(−0.59, −0.18)

< 0.001

0.00

(−0.54, 0.55)

0.988

Age (per year)

0.018

(0.010, 0.027)

< 0.001

0.011

(0.001, 0.020)

0.026

BMI

0.051

(0.031, 0.070)

< 0.001

−0.014

(−0.060, 0.033)

0.560

Weight (kg)

0.016

(0.009, 0.023)

< 0.001

0.007

(−0.015, 0.029)

0.535

Waist Circumference (cm)

0.023

(0.015, 0.031)

< 0.001

0.005

(−0.013, 0.023)

0.586

Mid Upper Arm Circumference (cm)

0.053

(0.027, 0.078)

< 0.001

0.006

(−0.044, 0.056)

0.824

HbA1c (%)

0.112

(0.023, 0.202)

0.014

0.045

(−0.044, 0.135)

0.317

Triglycerides (mmol/L)

0.110

(0.004, 0.216)

0.042

0.088

(−0.017, 0.193)

0.099

CAGE Score*

−0.160

(−0.318, −0.002)

0.047

0.061

(−0.113, 0.236)

0.490

Hip Circumference (cm)

0.016

(0.009, 0.023)

< 0.001

0.004

(−0.010, 0.017)

0.595

  1. LRTI lower respiratory tract infection, HbA1c glycated hemoglobin, % percentage, TB tuberculosis
  2. *CAGE, is a measure of hazardous alcohol use