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Table 3 Linear regression analysis for correlates of serum total cholesterol levels among people with HIV

From: Cotrimoxazole use is associated with lower total and non-high density lipoprotein cholesterol among people with HIV: a cross-sectional study

Characteristic

Crude β coefficient

95% CI

P-value

Adjusted β coefficient

95% CI

P-value

Currently on cotrimoxazole prophylaxis

 No

Ref

  

Ref

  

 Yes

−0.44

(−0.67,−0.21)

< 0.001

−0.18

(−0.35−0.01)

0.040

Sex

 Male

Ref

  

Ref

  

 Female

0.27

(0.07, 0.48)

0.009

0.08

(−0.15, 0.30)

0.504

Tribe

 Baganda

Ref

  

Ref

  

 Banyakitara

−0.31

(−0.56,−0.05)

0.020

−0.16

(−0.34, 0.02)

0.081

 Others

−0.08

(−0.37, 0.22)

0.612

−0.03

(−0.23, 0.18)

0.792

Dolutegravir

 No

Ref

  

Ref

  

 Yes

−0.40

(−0.78,−0.02)

0.041

0.07

(−0.21, 0.35)

0.630

At least one current opportunistic infection

 No

Ref

  

Ref

  

 Yes

−0.46

(−0.90,−0.01)

0.044

−0.03

(−0.34, 0.28)

0.839

Smoking

 Never smoked

Ref

  

Ref

  

 Formerly smoked (> 6 months)

−0.17

(−0.48, 0.14)

0.289

−0.14

(−0.37, 0.08)

0.209

 Currently smokes

−0.42

(−0.83,−0.02)

0.042

−0.06

(−0.34, 0.22)

0.676

Abnormalities on chest auscultation

 No

Ref

  

Ref

  

 Yes

−0.57

(−0.94,−0.20)

0.002

−0.39

(−0.65,−0.13)

< 0.001

Current lower respiratory tract infection

 No

Ref

  

Ref

  

 Yes

−0.22

(−0.42,−0.01)

0.038

−0.05

(−0.20, 0.11)

0.552

Age

0.02

(0.01, 0.03)

< 0.001

0.00

(−0.00, 0.01)

0.253

Duration on ART

0.04

(0.02, 0.05)

< 0.001

0.00

(−0.01, 0.01)

0.859

Weight

0.01

(0.01, 0.02)

< 0.001

0.09

(0.00, 0.17)

0.040

Body Mass Index

0.04

(0.02, 0.06)

< 0.001

−0.24

(−0.45,−0.03)

0.028

Waist circumference

0.02

(0.01, 0.03)

< 0.001

−0.15

(−0.28,−0.01)

0.032

Hip circumference

0.01

(0.01, 0.02)

< 0.001

0.00

(−0.02, 0.02)

0.942

Mid upper arm circumference

0.04

(0.02, 0.07)

0.001

0.02

(−0.01, 0.06)

0.226

Neck circumference

0.04

(0.01, 0.07)

0.016

0.04

(0.00, 0.07)

0.030

Systolic BP

0.01

(0.00, 0.01)

0.002

−0.01

(−0.01, 0.00)

0.135

Diastolic BP

0.01

(0.00, 0.02)

0.018

0.01

(−0.00, 0.02)

0.256

Fasting blood glucose

0.10

(0.02, 0.17)

0.014

0.04

(−0.02, 0.09)

0.160

HbA1c

0.12

(0.03, 0.21)

0.008

0.03

(−0.03, 0.09)

0.366

LDL-Cholesterol

0.73

(0.65, 0.81)

< 0.001

0.71

(0.63, 0.79)

< 0.001

HDL-Cholesterol

0.43

(0.23, 0.63)

< 0.001

0.62

(0.47, 0.76)

< 0.001

Triglycerides

0.17

(0.06, 0.27)

0.002

0.14

(0.07, 0.22)

< 0.001

Waist hip ratio

1.03

(0.01, 2.04)

0.048

−0.10

(−2.30, 2.09)

0.927

Waist Height ratio

3.51

(2.29, 4.72)

< 0.001

23.76

(2.37,45.15)

0.030

  1. LDL low density lipoprotein, HDL high density lipoprotein, HbA1c glycated hemoglobin, ART antiretroviral therapy, BP blood pressure, % percentage