Next-generation sequencing

Latest research

1. Genetic characterization of a Chinese cohort of suspected pediatric NF1 patients: a large-scale study using optimized whole-exome sequencing

   • Kaiyu Wang
   • Miao Jing
   • Quanze He

   in Journal of Human Genetics

   Article 10 December 2025

   

2. Analysis of genetic diversity and population structure of Gleditsia sinensis based on SLAF-Seq

   • Bing Yang
   • Jun Luo
   • Yayan Zhu

   in Genetic Resources and Crop Evolution

   Article 09 December 2025

   

3. Draft genome sequence of the pear pathogen Stemphylium vesicarium strain SVES21

   • Xueqin Chen
   • Chiara Fiorenzani
   • Riccardo Baroncelli

   in Journal of Plant Pathology

   Article 08 December 2025

4. TIRTL-seq: heroes with T-SHELL

   • Mary Melissa Roland
   • Alok V. Joglekar

   in Nature Methods

   Article 08 December 2025

   

5. An improved adaptive large neighborhood search algorithm for integrated scheduling of distributed production and distribution systems

   • Jiawen Deng
   • Jihui Zhang
   • Shengxiang Yang

   in Memetic Computing

   Article 08 December 2025

   

6. Optimism for abundant whole-brain connectomes and connectomic screening

   • Moritz Helmstaedter

   in Nature Methods

   Article 08 December 2025

   

7. Harnessing genomic technologies for modern soybean breeding

   • Chae Won Yoon
   • Yejin Kang
   • Ju-Kyung Yu

   in Journal of Crop Science and Biotechnology

   Article 08 December 2025

8. Accelerating GridSearchCV hyperparameter tuning method using an FPGA-based hardware accelerator

   • Arian Shahbazian
   • Mohammadreza Binesh Marvasti
   • Seyyed Amir Asghari

   in The Journal of Supercomputing

   Article 06 December 2025

   

9. Repository-level code completion with adaptive segmentation and fused retrieval

   • Yuanyuan Shen
   • Pinle Qin
   • Guiji Li

   in Empirical Software Engineering

   Article 05 December 2025

   

10. Intra-strain genetic heterogeneity in Toxoplasma gondii ME49: Oxford Nanopore long-read sequencing reveals copy number variation in the ROP8-ROP2A locus

    • Yomna Gohar
    • Marie Neumann
    • Alexander Dilthey

    in BMC Genomics

    Article Open access 03 December 2025

    

11. Vina-FPGA2: a high-level parallelized hardware-accelerated molecular docking tool based on the inter-module pipeline

    • Ming Ling
    • Shidi Tang
    • Yanxiang Zhu

    in Frontiers of Information Technology & Electronic Engineering

    Article 03 December 2025

12. Die Next Generation der DGI: Ganz nah dran, an den Bedürfnissen des Nachwuchses

    in ZI Zahnärztliche Implantologie

    Article 02 December 2025

    

13. High resolution melting real-time PCR for genotyping of Giardia lamblia assemblages A and B regardless of parasite load

    • Monique Pinto-Gonçalves
    • Beatriz Iandra da Silva Ferreira
    • Maria Fantinatti

    in Gut Pathogens

    Article Open access 02 December 2025

    

14. A prospective, multicenter, comprehensive genomic profile signature study in patients with EGFR-mutant advanced non-small cell lung cancer at the first-line treatment failure of osimertinib

    • Yuankai Shi
    • Dongqing Lv
    • Yong Zhang

    in Signal Transduction and Targeted Therapy

    Article Open access 02 December 2025

    

15. Evaluation of false positive and false negative errors in targeted next generation sequencing

    • Youngbeen Moon
    • Young-Ho Kim
    • Kyeong-Man Hong

    in Genome Biology

    Article Open access 01 December 2025

    

16. Neues Verschlüsselungsverfahren für Telematikinfrastruktur

    • Rebekka Höhl

    in DNP – Die Neurologie & Psychiatrie

    Article 01 December 2025

    

17. Application of metagenomic next-generation sequencing technology in hematologic malignancy patients with sepsis following antibiotic use

    • Bingrong Chen
    • Wenxiu Shu
    • Dian Jin

    in BMC Infectious Diseases

    Article Open access 01 December 2025

    

18. Exploratory analysis of the molecular and genomic landscape of upper tract urothelial carcinoma using long-read sequencing

    • Zhi Shang
    • Xiuxin Ling
    • Dingwei Ye

    in BMC Cancer

    Article Open access 01 December 2025

    

19. HAlign-G: rapid and low-memory multiple-genome aligner for large-scale closely related genomes

    • Pinglu Zhang
    • Tong Zhou
    • Ximei Luo

    in Genome Biology

    Article Open access 28 November 2025

    

20. Classifying the tumor immune microenvironment in cervical cancer based on nuclear cytoplasmic consistent genes

    • Jiawei Wang
    • Anji Chen
    • Jun He

    in Scientific Reports

    Article Open access 28 November 2025

    

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