Clinical Trials

Latest research

1. Preclinical pancreatic cancer mouse models for treatment with small molecule inhibitors: a systematic review and meta-analysis

   • Sophia Villwock
   • Yalda Mirzaei
   • Julia Steitz

   in Scientific Reports

   Article Open access 27 October 2025

   

2. Accelerating the translation of findings from the MoTrPAC study to benefit clinical care: a qualitative analysis

   • Katherine A. Collins-Bennett
   • Kandice R. Lacci-Reilly
   • Dan M. Cooper

   in BMC Primary Care

   Article Open access 27 October 2025

   

3. Patientenzentrierte Endpunkte in der Onkologie: Patient-Reported Outcomes in Studien der Arbeitsgemeinschaft Internistische Onkologie (AIO)

   • Tabea Fröhlich
   • Tessa Lehmann
   • Sabrina Sulzer

   in Die Onkologie

   Article 27 October 2025

   

4. Awareness of Decentralized Clinical Trials (DCT) in patients with type 2 diabetes

   • Subramani Poongothai
   • Ranjit Mohan Anjana
   • Viswanathan Mohan

   in International Journal of Diabetes in Developing Countries

   Article 26 October 2025

   

5. Efficacy of Lactococcus lactis Strain Plasma in Patients with Mild COVID-19: A Multicenter, Double-Blinded, Randomized-Controlled Trial (PLATEAU Study)

   • Kazuko Yamamoto
   • Tsuyoshi Inoue
   • Hiroshi Mukae

   in Infectious Diseases and Therapy

   Article Open access 25 October 2025

   

6. Other adverse reaction research

   in Reactions Weekly

   Article 25 October 2025

7. A Multicenter, Prospective, Observational, and Single-Arm Interventional Study of Mirogabalin in Diabetic Peripheral Neuropathic Pain: Rationale and Design of Dia-NeP

   • Hideki Kamiya
   • Ryo Suzuki
   • Jiro Nakamura

   in Diabetes Therapy

   Article Open access 24 October 2025

   

8. Memantine: updates from the past decade and implications for future novel therapeutic applications

   • Wojciech Danysz
   • Niels Hansen
   • Andreas Gravius

   in Journal of Neural Transmission

   Article Open access 24 October 2025

   

9. Physiotherapie als häufigste Vortherapie bei chronischen Rückenschmerzen

   • Redaktion Facharztmagazine

   in Schmerzmedizin

   Article 24 October 2025

10. Clinical added value of LAFOV PET/CT in patients undergoing same-day [18 F]FDG SAFOV PET/CT scans: an initial experience report and explorative study

    • Martina Di Franco
    • Andrea Di Giorgio
    • Stefano Fanti

    in European Journal of Nuclear Medicine and Molecular Imaging

    Article Open access 24 October 2025

    

11. Assessing new treatments for central sleep Apnoea in heart failure: sample size considerations for reliable detection of safety signals

    • Holger Woehrle
    • Karl Wegscheider
    • Martin R. Cowie

    in Sleep and Breathing

    Article Open access 23 October 2025

    

12. Reevaluating the Design of Multicenter Surgical Trials for Esophagogastric Cancer

    • Bibek Das
    • Anuja T. Mitra
    • George B. Hanna

    in Annals of Surgical Oncology

    Article Open access 23 October 2025

    

13. Progress in Clinical Trials of CDK4/6 Inhibitors

    • Takae Mizukami
    • Alberto J. Montero

    in Current Breast Cancer Reports

    Article Open access 22 October 2025

14. Rationale and study design of a randomized controlled trial to investigate the effect of romosozumab on bone mineral density in hemodialysis patients with osteoporosis (the TRINITY study): A study protocol

    • Toshihiro Mizukoshi
    • Yachiyo Kuwatsuka
    • Sawako Kato

    in Renal Replacement Therapy

    Article Open access 21 October 2025

    

15. Estimating comparative effectiveness using Single-Arm trials: A challenge in the field of agnosticism

    • Shang Cao
    • Hongwei Kan
    • Jianhong Pan

    in BMC Medical Research Methodology

    Article Open access 21 October 2025

    

16. Pimavanserin

    in Reactions Weekly

    Article 18 October 2025

17. Other adverse reaction research

    in Reactions Weekly

    Article 18 October 2025

18. The second interim analysis of Italian participants enrolled in the real-world, Pan-European, prospective, observational, Phase 4 PEARL study of fremanezumab effectiveness

    • Fabrizio Vernieri
    • Anna Ambrosini
    • Mario Cepparulo

    in Neurological Sciences

    Article Open access 17 October 2025

    

19. Drug repurposing in oncology: a systematic review of anticancer effects of Lanatoside C at the molecular level

    • Oluwatobi O. Olayode
    • Tolulope J. Oladosu
    • Blessing T. Ogunoye

    in BMC Cancer

    Article Open access 17 October 2025

    

20. Effectiveness, cost-effectiveness, and return on investment of the web-based MiLES intervention targeted at employers, to enhance successful return to work of employees with cancer: design of a randomized controlled trial

    • Judith M. Mollet
    • Michiel A. Greidanus
    • Sietske J. Tamminga

    in Trials

    Article Open access 16 October 2025

    

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