Blood-Brain Barrier

Latest research

1. The border-associated macrophage marker MRC1 contributes to an early neuroprotective inflammatory response to traumatic brain injury in mice

   • Jenny Strehle
   • Pawit Somnuke
   • Michael K. E. Schäfer

   in Acta Neuropathologica Communications

   Article Open access 30 October 2025

   

2. The role of ROCK1/MLC/NMMHC IIA-actin signaling in ischemic stroke-induced blood-brain barrier disruption: implications for therapeutic intervention

   • Liangying Bao
   • Yuanhao Xu
   • Junping Kou

   in Cellular and Molecular Life Sciences

   Article Open access 30 October 2025

   

3. TNF-α in traumatic brain injury: a bidirectional effect in regulating neuroimmune and inflammatory responses

   • Meng Zhang
   • Jiangang Xie
   • Wen Yin

   in Cellular and Molecular Life Sciences

   Article Open access 30 October 2025

   

4. Comparative analysis of the uptake of the H⁺/OC antiporter substrate oxycodone across and into brain endothelial and parenchymal cells with in vitro–in vivo extrapolation

   • Frida Bällgren
   • Nana Svane
   • Irena Loryan

   in Fluids and Barriers of the CNS

   Article Open access 30 October 2025

   

5. DeepB³Pred: blood–brain barrier peptide predictor using stacked BiGRU model with novel features

   • Muhammad Arif
   • Saleh Musleh
   • Tanvir Alam

   in BMC Biology

   Article Open access 29 October 2025

   

6. Leveraging quantum chemical properties in transfer learning for predicting blood-brain barrier permeability of drugs

   • Megan A. Lim
   • Marybeth G. Yonk
   • Kecheng Lei

   in Drug Delivery and Translational Research

   Article 29 October 2025

   

7. Modulation of the blood–brain barrier permeability by patient-derived glioblastoma stem cell secretome

   • Francesco Saverio Sica
   • Michela Patrucco
   • Francesca Re

   in Scientific Reports

   Article Open access 27 October 2025

   

8. Utility of SIRS criteria and QSOFA score in identifying patients with central nervous system infections at risk for poor outcome

   • Yannick C. Resok
   • Sabine E. Olie
   • Matthijs C. Brouwer

   in Scientific Reports

   Article Open access 27 October 2025

   

9. A bridge over troubled water? Bridging-Lyse bei Schlaganfall mit proximalem Gefäßverschluss

   • Frank Stachulski

   in CardioVasc

   Article 24 October 2025

10. Angiotensin III induces disruption of blood-brain barrier integrity in vitro in bEnd.3 brain endothelial cells

    • Ecem Ayvaz
    • Ahmet Umur Topçu
    • Mehmet Kaya

    in Hypertension Research

    Article 24 October 2025

    

11. Abspeckmittel lindert Migräne

    • Thomas Müller

    in CardioVasc

    Article 24 October 2025

    

12. Outcome in adult patients with severe TBI, using a management protocol allowing a cerebral perfusion pressure ≤ 60 mmHg – a retrospective study over 10 years

    • Linus Réen
    • Anna Radman
    • Peter Siesjö

    in Acta Neurochirurgica

    Article Open access 23 October 2025

    

13. Biomarker für Insulinresistenz des Gehirns im Blut entdeckt

    • Birgit Niesing

    in Info Diabetologie

    Article 23 October 2025

    

14. QbD-Optimized Quercetin-Loaded Cationic SLNs Enhance Neuroprotection in H₂O₂-Induced Alzheimer’s Zebrafish Model

    • Gurisha Garg
    • Arti Singh
    • Balak Das Kurmi

    in BioNanoScience

    Article 21 October 2025

    

15. A Comprehensive Review of Nanoemulsion Via the Nose To the Brain in the Management of Parkinson’s Disease

    • Hitendra Mahajan
    • Rahul Sarode
    • Swati Khedekar

    in Journal of Pharmaceutical Innovation

    Article 21 October 2025

    

16. Oraler CGRP-Rezeptor-Antagonist reduziert Prodromalsymptome

    • Hans-Christoph Diener

    in InFo Neurologie + Psychiatrie

    Article 20 October 2025

17. Bruton-Tyrosinkinase-Inhibitor bremst die Entzündungsaktivität

    • Ralf Gold

    in InFo Neurologie + Psychiatrie

    Article 20 October 2025

18. APOE ε4 erhöht das Risiko für intrakranielle Blutungen unter Apixaban

    • Gerrit M. Große

    in InFo Neurologie + Psychiatrie

    Article 20 October 2025

19. Evaluation of Sirtuin 1 (SIRT1) and Sirtuin 3 (SIRT3) in serum and cerebrospinal fluid following fatal traumatic brain injury

    • Łukasz A. Poniatowski
    • Agnieszka Siwińska
    • Mieszko Olczak

    in International Journal of Legal Medicine

    Article Open access 18 October 2025

    

20. Stereotactic radiosurgery for patients with extensive brain metastases across the disease course

    • Tina Vaziri
    • I-Chia Liu
    • Kristin J. Redmond

    in Journal of Neuro-Oncology

    Article 16 October 2025

    

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