A TEMPO-loaded DNA hydrogel enabling integrated early diagnosis and treatment of osteoarthritis Hong HuangMingze TangGuangfeng Ruan Research Open access 31 October 2025 Article: 695
Programmed nanozyme hydrogel enabling spatiotemporal modulation of wound healing achieves skin regeneration after biofilm infection Ze-Ming ZhuangYi WangWei-Qiang Tan Research Open access 31 October 2025 Article: 694
Transcranial and precise optical neuromodulation mediated by NIR photoactive nanosheets Deqi YangYa ZhangYin Fang Research Open access 29 October 2025 Article: 693
Recent advances in theranostic nanomaterials for overcoming traumatic brain injury Nam Cheol HwangDong Min LimDokyoung Kim Review Open access 29 October 2025 Article: 692
Enhanced atherosclerosis molecular imaging and therapy with collagen hybridizing peptide functionalized albumin nanoparticles Jianan HeJianxun CaiPengfei Pang Research Open access 28 October 2025 Article: 691
Dual-function MgSrCeAl-LDH nanosheets enable both ROS clearance and enhanced angiogenesis for myocardial ischemia/reperfusion injury therapy Jiayi ShenYuwen LuoLingchun Lyu Research Open access 27 October 2025 Article: 690
An endoplasmic reticulum stress-responsive nanocomposite hydrogel for diabetic wound healing through a fibroblast-immune cell dual regulation hub Shaoying GaoTao ChenZairong Wei Research Open access 24 October 2025 Article: 689
Amorphous layered double hydroxide-based nano-enzyme eye drops against dry eye disease by inhibiting mitochondrial damage and pyroptosis Dandan ChuTingting HuJingguo Li Research Open access 22 October 2025 Article: 688
Platelet-derived biomimetic nanoplatforms: a promising drug delivery strategy for cardiovascular disease Simin ZhangMei HanPan Liang Review Open access 21 October 2025 Article: 687
Electron-injected Pd@CeO2 nanozymes for multifaceted ROS scavenging and protection against ischemia-reperfusion injury in skin flaps Lingling ZhouJiayuan SunYuehua Li Research Open access 21 October 2025 Article: 686
Micro/nano motors treating of digestive system diseases Yang YaoLan LiuWeifang Liao Review Open access 16 October 2025 Article: 685
Fe-doped phase-transition nanodroplets for synergistic photothermal and starvation-enhanced ferroptosis in cancer therapy Yuhang TianXiang HeHui Jing Research Open access 16 October 2025 Article: 684
Dendritic cell-targeted liposomes for cancer immunotherapy via inhibition of aryl hydrocarbon receptor Chen-Guang ZhangChen-Yun YehYungling Leo Lee Research Open access 15 October 2025 Article: 683
Engineered GLP-1R-targeting nanoplatforms: multimodal therapeutics in human diseases Juan ZengXinxin TangAnguo Wu Review Open access 15 October 2025 Article: 682
A novel ligustrazine-based nanodelivery system protects against doxorubicin-induced cardiotoxicity by targeting the SIRT5–DUSP1 axis for mitochondrial repair Hongshuo ShiBoxian PangXing Chang Research Open access 15 October 2025 Article: 681
Investigation of the effects of Si-A/PUE@HA hydrogels on the osteochondral defect microenvironment based on single-cell RNA sequencing Zhipeng XiNing XuJingchi Li Research Open access 15 October 2025 Article: 680
Mesenchymal stem cell-derived apoptotic vesicles: emerging cell-free strategy for periodontitis treatment Jingru HanYinyin HuangLan Yang Review Open access 15 October 2025 Article: 679
Advances of extracellular vesicles isolation and detection frontier technology: from heterogeneity analysis to clinical application Bei LiWei WuCheng Ji Review Open access 14 October 2025 Article: 678
Neuron-targeted ROS-responsive liposomes for puerarin delivery remodel ischemic microenvironment via microglial modulation and neurovascular regeneration Di ChenHui JiangShaohua Li Research Open access 14 October 2025 Article: 677
Extracellular vesicles in metabolic perspective: mechanism and targeted therapy Qifeng ShengZebin WuDechun Geng Review Open access 14 October 2025 Article: 676
Programmable macrophage-polarizing nanoparticles for MRI-guided early detection and treatment of pulmonary metastases Meiju SuiKairu XieXin Zhou Research Open access 14 October 2025 Article: 675
Correction: Single‑cell multi‑omics analysis reveals the mechanism of action of a novel antioxidant polyphenol nanoparticle loaded with STAT3 agonist in mediating cardiomyocyte ferroptosis to ameliorate age‑related heart failure Haoyuan ZhengYuan TianYanxiao Liang Correction Open access 14 October 2025 Article: 674
Decellularized extracellular matrix bio-patch with strong and biodegradable wet adhesive interface for sutureless soft tissue defect repair Xiaoya ChenBinbin GuanZuoying Yuan Research Open access 14 October 2025 Article: 673
Lipid metabolism and lipid signaling in extracellular vesicles ontogeny: from biogenesis to functional execution Jiaxin ZhangJiali LiZixuan Sun Review Open access 14 October 2025 Article: 672
Programmable metal-based immuno-photocatalytic nanoparticles for precision activation of anti-tumor immunity Tianbo LiuLing YangYingnan Yang Review Open access 14 October 2025 Article: 671
Biomimetic ferritin nanocages for synergistic co-delivery of metformin and rapamycin restore neurodevelopmental homeostasis in autism spectrum disorders Yizhe ShenLele YuShini Feng Research Open access 14 October 2025 Article: 670
Nanotechnology-driven biofortification of Fe, Zn, and Se in edible plants Luana Vanessa Peretti MinelloSuelen Goettems KuntzlerRaul Antonio Sperotto Review Open access 14 October 2025 Article: 669
Integrating artificial intelligence with nanodiagnostics for early detection and precision management of neurodegenerative diseases Youssef M. HassanAhmed WanasWael M. El-Sayed Review Open access 13 October 2025 Article: 668
Nanobody Immunolabelling and three-dimensional imaging reveals spatially restricted LYVE1 expression by kidney lymphatic vessels in mice Eva Maria FunkDaniyal J. JafreeRené Hägerling Research Open access 13 October 2025 Article: 667
Harnessing smart nanomaterials to reprogram neutrophil plasticity in immune modulation Jiaxin LuoJingxia ChenYanmin Zhou Review Open access 11 October 2025 Article: 666
Tungsten disulfide atomic crystals with RONS scavenging and liver targeting capabilities for acetaminophen-induced acute liver injury therapy Ziwen XiaoYu LiuDeyan Gong Research Open access 11 October 2025 Article: 665
Nanomedicine targeting the PD-1/PD-L1 axis in autoimmune diseases: breaking conventional barriers to restore immune tolerance Gang XiangYuanxu CuiXing Zhou Review Open access 11 October 2025 Article: 664
Nanopore-based sensing for biomarker detection: from fundamental principles to translational diagnostics Narlawar Sagar ShrikrishnaSonu Gandhi Review Open access 11 October 2025 Article: 663
Spontaneous hydrogen-releasing nanoenzyme alleviates osteoarthritis via oxidative stress reduction and mitochondrial dysfunction reversal Qi WangMinyi ZhangChengqing Yi Research Open access 11 October 2025 Article: 662
PDLIM4 drives gastric cancer malignant progression and cisplatin resistance by inhibiting HSP70 ubiquitination and degradation via competitive interaction with STUB1 Chao ZhuMeng ChenAiping Le Research Open access 11 October 2025 Article: 661
Orally administered degradable nanoarmor-assisted probiotics for remodeling the gut microenvironment and treating osteoporosis Zhiqiang LiXueqiang DengJun Luo Research Open access 11 October 2025 Article: 660
Customized extracellular vesicles targeting lysosomal biogenesis deliver therapeutic cargo for intervertebral disc degeneration treatment Zhiwei LiaoZixuan OuCao Yang Research Open access 11 October 2025 Article: 659
Manganese-loaded carbon nanoparticles ameliorate ANCA-associated vasculitis by inhibiting ferroptosis Yiru WangYongman LvQingquan Liu Research Open access 10 October 2025 Article: 658
Drug loaded cerium oxide nanozymes prevent radiation-Induced cataracts via suppressing the cGAS-STING pathway Qifang ChenPeilin GuChongyi Li Research Open access 10 October 2025 Article: 657
A novel scalable method for the production of rennet-treated milk-derived extracellular vesicles for improved curcumin oral delivery Emily SchifanoFrancesco VariStefano Tacconi Research Open access 10 October 2025 Article: 656
Constructing biomimetic microenvironments for liver regeneration Yawen ZhuWanqi YangHaozhen Ren Review Open access 10 October 2025 Article: 655
Scientometric analysis of extracellular vesicles in vision science (up to 2024) Fei LiaoFrancisco GermainTing Wang Review Open access 10 October 2025 Article: 654
Targeting ferroptosis to rescue osteogenic differentiation in BRONJ-affected jawbone mesenchymal stem cells: the role of miR-145-3p and exosome-mediated therapy Yi ShuaiBo ChenLei Jin Research Open access 10 October 2025 Article: 653
ROS-degradable hydrogel delivering LOXL2-LNPs rescues disc degeneration by synchronously suppressing cellular senescence and oxidative damage Jian ZhangYang LiXigao Cheng Research Open access 10 October 2025 Article: 652
Cascade-targeting copper homeostasis nano-regulators for mild-photothermal boosted cuproptosis/ferroptosis mediated breast cancer therapy Xuejun LiangShiji FangXin Liu Research Open access 10 October 2025 Article: 651
Photothermal nano-agents: an innovative trident weapon for accurate and effective treatment of alzheimer’s disease Jianfei ChenXiaowei ZhangCan Wu Review Open access 10 October 2025 Article: 650
Targeting JAK2 with a multifunctional nanoinhibitor for long-lasting anti-inflammatory effects and bone repair Yang LiuDuan WangXiaowei Xu Research Open access 10 October 2025 Article: 649
Fe-MOF loaded with capmatinib to reverse immunosuppressive microenvironment and inhibit tumor metastasis after radiofrequency ablation Jinchao ZhaoLei LeiZhe Tang Research Open access 10 October 2025 Article: 648
Rational engineering of nanoplatforms with hierarchical targeting hepatic tumor and subcellular mitochondria for enhanced image-guided photodynamic therapy Xiaofei ShangWenjie ShaoTingting Zhao Research Open access 10 October 2025 Article: 647
Neuroprotective effects of Berberine-loaded BMSCs-apoptotic extracellular vesicles on retinal ganglion cells: therapeutic potential for glaucomatous injury Mengling YouXuan ZhangXiaobo Xia Research Open access 10 October 2025 Article: 646