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Fig. 1 | Critical Care

Fig. 1

From: Therapeutic plasma exchange in amatoxin associated acute liver failure–results from the multi-center Amanita-PEX study

Fig. 1

Flow chart of study participants. Shown are pre-screening, screening, inclusion and analysis of patients. Included were patients with the diagnosis of acute liver failure following laboratory confirmed Amatoxin ingestion. The diagnosis of acute liver failure was made according to the European Association for the Study of the Liver (EASL) criteria in patients with severe acute liver injury, indicated by the presence of both coagulopathy (international normalized ratio [INR] > 1.5) and manifest hepatic encephalopathy, without pre-existing chronic advanced liver disease. The study compared standard of care (SOC) with SOC + therapeutic plasma exchange (PEX). This was a retrospective, multicenter, multi-national, real-world study

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