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Table 1 Demographic and clinical characteristics of post mortem cases used in the study

From: Alzheimer’s disease pathology propagation by exosomes containing toxic amyloid-beta oligomers

Diagnosis

Age

Sex

PMI

Braak

Thal

CERAD

NIA-Reagan

αSyn

AD

61

F

48

5–6

5

C

High prob

None

AD

64

M

12

5–6

5

C

High prob

None

AD

85

F

21

5–6

3

B

High prob

None

AD

90

F

11

5

3

B

 

None

AD

63

F

48

6

5

C

 

None

C

88

M

39

0

0

0

 

None

C

88

F

22

2

0

0

 

In S Nigra

C

63

M

30

0

0

0

 

None

C

90

M

30

0

1

0

 

None

C

91

M

27

3

4

C

 

None

  1. 5 severe Alzheimer’s disease cases (Braak stages V–VI) and 5 nondemented cases (Braak stages 0–III) were used to determine the presence of oAβ in brain derived exosomes