Data and Code for “Monitoring in Real Time and Far-Red Imaging of H₂O₂ Dynamics with Subcellular Resolution”
dataset
posted on 2025-02-04, 23:53 authored by Justin Daho LeeJustin Daho Lee, Amanda Nguyen, Chelsea E. Gibbs, Zheyu Ruby Jin, Yuxuan Wang, Aida Moghadasi, Sarah J. Wait, Hojun Choi, Kira M. Evitts, Anthony Ascencio, Samantha B Bremner, Shani Zuniga, Vedant Chavan, C. Andrew Williams, Annette Smith, Farid Moussavi-Harami, Michael Regnier, David Baker, David L Mack, Elizabeth Nance, Patrick M BoylePatrick M Boyle, Andre BerndtAndre Berndt<p dir="ltr"><b>Description:</b></p><p dir="ltr">This dataset contains the <b>code, data, and computational resources</b> used to generate the results presented in the paper <b>“Monitoring in Real-Time and Far-Red Imaging of H₂O₂ Dynamics with Subcellular Resolution.”</b></p><p dir="ltr"><b>Contents:</b></p><ul><li><b>Conda Environment</b> – Environment configuration to ensure reproducibility.</li><li><b>Data, Visualization, and Detailed Statistics</b> – Raw data and statistical analysis for <b>main and supplementary figures</b>.</li><li><b>ColabFold Prediction Structures</b> – Computationally predicted protein structures.</li><li><b>Analysis Code for Immunofluorescence (IF) Data</b> – Scripts for quantifying <b>nuclear translocation</b>.</li><li><b>Computational Cell-Scale Modeling Code</b> – Simulations for modeling <b>hiPSC-CMs</b> at the cellular level.</li><li>This upload provides all necessary materials to <b>reproduce the analysis and visualizations</b> presented in the study.</li></ul><p dir="ltr">For any inquiries, please contact:</p><p dir="ltr">Justin Daho Lee([email protected]), Andre Berndt(Correspondence, [email protected])</p>
