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Searching for putative virulence factors in the genomes of Shewanella indica and Shewanella algae

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Bacterial pathogens are a major threat to both humans and animals worldwide. It is crucial to understand the mechanisms of various disease processes at the molecular level. Shewanella species are widespread in the environment and some are considered as emerging opportunistic human and marine mammal pathogens. In this study, putative virulence factors on the genome of Shewanella indica BW, a bacterium isolated from the Bryde’s whale (Balaenoptera edeni), were determined. Additionally, for comparative purposes, putative virulence factors from two other S. indica and ten S. algae strains were also determined using the Pathosystems Resource Integration Center (PATRIC) pipeline. We confirmed the presence of previously reported virulence factors and we are proposing several new candidate virulence factors. Interestingly, the putative virulence factors were very similar between the two species with the exception of microbial collagenase which was present in all S. algae genomes, but absent in all S. indica genomes.

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Acknowledgements

This research was done as part of a Provost Honors project under the leadership of Zina Haywood, Executive Vice President/Provost. We thank Jorge Nieto and Donald Zakutansky for their enthusiastic support of this research.

Funding

This work was supported by grants from the Bureau of Science & Technology for Development, the Chinese Academy of Sciences (No. ZSSD-004), and the National Natural Science Foundation of China (No. 31870372).

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Authors and Affiliations

  1. General Studies, Gateway Technical College, Kenosha, WI, 53144, USA

    Alazea M. Tamez & Richard William McLaughlin

  2. The Key Laboratory of Aquatic Biodiversity and Conservation of the Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, 430072, China

    Richard William McLaughlin, Jia Li, XiaoLing Wan & JinSong Zheng

  3. University of Chinese Academy of Sciences, Beijing, 100049, China

    Jia Li

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  1. Alazea M. Tamez
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  2. Richard William McLaughlin
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  3. Jia Li
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Contributions

JZ and RWM designed this project. JL, XW, and JZ were responsible for genomic sequencing and data collecting. AMT and RWM analyzed data. AMT, RWM, and JZ wrote the manuscript. All authors contributed to discussions and revisions, and approved the final manuscript.

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Correspondence to JinSong Zheng.

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Tamez, A.M., McLaughlin, R.W., Li, J. et al. Searching for putative virulence factors in the genomes of Shewanella indica and Shewanella algae. Arch Microbiol 203, 683–692 (2021). https://doi.org/10.1007/s00203-020-02060-1

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