Summary
The ENA2 gene encoding a P-type ATPase involved in Na+ and Li+ effluxes in Saccharomyces cerevisiae has been isolated. The putative protein encoded by ENA2 differs only in thirteen amino acids from the protein encoded by ENA1/PMR2. However, ENA2 has a very low level of expression and for this reason did not confer significant Li+ tolerance on a Li+ sensitive strain. ENA1 and ENA2 are the first two units of a tandem array of four highly homologous genes with probably homologous functions.
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Communicated by C.P. Hollenberg
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Garciadeblas, B., Rubio, F., Quintero, F.J. et al. Differential expression of two genes encoding isoforms of the ATPase involved in sodium efflux in Saccharomyces cerevisiae . Molec. Gen. Genet. 236, 363–368 (1993). https://doi.org/10.1007/BF00277134
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DOI: https://doi.org/10.1007/BF00277134