Protection Against Nematodes by Intestinal Mucus

Miller, H. R. P.; Huntley, J. F.

doi:10.1007/978-1-4615-9254-9_37

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 144))

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Abstract

Several lines of evidence suggest that intestinal mucus is involved in protection against nematode infections (Miller and Nawa, 1979). For example, Trichinella spiralis larvae become entrapped in mucus both in vivo in immune rats and in vitro (Lee and Ogilvie, 1980). Similarly, the immune expulsion of Njppostronqylus brasiliensis from rat intestine is accompanied by goblet cell hyperplasia and increased turnover of mucin (Miller et al., 1981). The experiments described here provide further information on the role of mucus in protection against N. brasiliensis.

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References

Miller, H.R.P., and Nawa, Y., 1979, Immune regulation of goblet cell differentiation, specific induction of non specific protection against helminths? Nouv. Rev. Fr. Hematol., 21: 31
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Lee, G.B., and Ogilvie, B.M., 1980, The mucus layer in intestinal nematode infections, in: ‘Mucosal immune system in health and disease, report of 81st Conference on pediatric research’ Ogra, P.L. and Bienenstock, J., Ed., (in press).
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Miller, H.R.P., Huntley, J. F., and Dawson, A. McL., 1981, Mucus secretion in the gut, its relationship to the immune response in Nippostrongylus infected rats, in: ‘Current Topic in Veterinary Medicine and Animal Science’, Bourne, F. J., ed., Martinus and Nijhoff, London and The Hague (in press).
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Authors and Affiliations

Department of Pathology, Animal Diseases Research Association, Moredun Institute, 408 Gilmerton Road, Edinburgh, EH17 7JH, UK
H. R. P. Miller & J. F. Huntley

Authors

H. R. P. Miller
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J. F. Huntley
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Editors and Affiliations

Department of Obstetrics and Gynecology, University Hospital of South Manchester, Manchester, England
Eric N. Chantler & Max Elstein &
University of Department of Surgery, Manchester Royal Infirmary, Manchester, England
James B. Elder

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Miller, H.R.P., Huntley, J.F. (1982). Protection Against Nematodes by Intestinal Mucus. In: Chantler, E.N., Elder, J.B., Elstein, M. (eds) Mucus in Health and Disease—II. Advances in Experimental Medicine and Biology, vol 144. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9254-9_37

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DOI: https://doi.org/10.1007/978-1-4615-9254-9_37
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4615-9256-3
Online ISBN: 978-1-4615-9254-9
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