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A catalyst for better

March 26, 2025

A catalyst for better

Image credit: PLOS

09/19/2025

Research Article

Psilocybin-assisted group psychotherapy and mindfulness-based stress reduction for frontline healthcare provider COVID-19-related depression and burnout: A randomized controlled trial

Benjamin Lewis and colleagues explore the therapeutic use of psilocybin coupled with mindfulness training compared with mindfulness training alone to tackle burnout and depression in healthcare providers in a randomized controlled study.

Image credit: Mulyadi; unsplash

Psilocybin-assisted group psychotherapy and mindfulness-based stress reduction for frontline healthcare provider COVID-19-related depression and burnout: A randomized controlled trial

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09/18/2025

Research Article

Dihydroartemisinin–piperaquine plus sulfadoxine–pyrimethamine versus either drug alone for intermittent preventive treatment of malaria in pregnancy: A double-blind, randomized, controlled phase 3 trial from Uganda

In a randomized clinical trial of two drug regimens for intermittent preventive treatment of malaria in pregnancy (IPTp), Abel Kakuru and colleagues report that, unexpectedly, combining the two regimens did not result in fewer adverse birth outcomes than either regimen alone. 

Image credit: Alex Green, pexels

Dihydroartemisinin–piperaquine plus sulfadoxine–pyrimethamine versus either drug alone for intermittent preventive treatment of malaria in pregnancy: A double-blind, randomized, controlled phase 3 trial from Uganda

09/19/2025

Perspective

A need for new tools for prevention of malaria in pregnancy

Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is a chemoprevention strategy against malaria in pregnancy. This Perspective highlights a recent PLOS Medicine study which demonstrates the need for better understanding of the mechanism by which IPTp-SP works, as well as novel measures to prevent malaria earlier in gestation.

Image credit: João Paulo de Souza Oliveira, pexels

A need for new tools for prevention of malaria in pregnancy

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