The Journal of Headache and Pain is a peer-reviewed open access journal specifically dedicated to researchers involved in all aspects of headache and related pain syndromes, including epidemiology, public health, basic science, translational medicine, clinical trials and real-world data. With a multidisciplinary perspective, The Journal of Headache and Pain covers headache medicine and related pain syndromes in all medical disciplines and particularly encourages clinical, translational and basic science submissions in the areas of pain management, genetics, neurology and internal medicine. Read more.
Featured Articles: September, 2025
Call for papers
Focus China
Edited by: Jin Tao, Yiheng Tu, and Yonggang Wang
This Collection provides a dedicated platform for researchers and clinicians primarily affiliated with Chinese institutions to share their insights and contribute to the global knowledge of headache science while addressing the specific needs of their region.
Pathophysiology of Pain in Neurodegenerative Diseases
Edited by: Adriana Della Pietra and Rashid Giniatullin
This Collection invites original papers and review articles primarily devoted to understanding pathophysiological mechanisms linking various types of pain, including migraine, headache and other pain syndromes, with neurodegenerative disorders.
The Epigenome and Transcriptome in Headache Disorders
Edited by: Michał Fila and Wei Wang
This Collection focuses on the latest advancements in the studies on the epigenome and transcriptome in headache research, aiming to elucidate the complex neurological mechanisms underlying headache disorders, particularly migraine and tension-type headaches.
Community pharmacy and headache care
Edited by: Timothy J Steiner, Damiana Scuteri and Heba Bani Hani
Community pharmacists are an underutilized resource, potentially well able to provide the solution. The collection highlights studies on current pharmacy practice (scope, responsibilities and regulatory and other restrictions) relevant to headache care in countries worldwide.
Focus Africa
Edited by: Mendinatou Agbetou Houessou, Najib Kissani and Mona Nada
This Collection provides a dedicated platform for African researchers and clinicians to contribute to global headache science while addressing the specific needs of the region.
Brain and Mind
Edited by: Alberto Raggi and Sheila Crewther
This collection aims to gather the most innovative research on the biopsychosocial perspective in headache and pain.
Migraine and Brain Health: Towards Better Understanding from the Asia-Oceania Region
Edited by: Tissa Wijeratne, Sophie Merve Yener and Lakshman Singh
This collection highlights migraine and brain health in the Asia-Oceania region, exploring its impact across the lifespan. We welcome research on new treatments, cultural factors, and digital health solutions. Contribute to advancing migraine care and brain health in this unique region.
AI Advancements in Headache Research: Navigating the Digital Frontier
Edited by: Gianluca Coppola and Igor Petrušić
This collection explores the use of machine learning in migraine research, focusing on advanced algorithms and computational techniques to analyze clinical and neuroimaging data, aiming to uncover patterns and relationships with digital twin solutions.
Article collections
Click here to see the article collections and thematic series that the journal has published in recent years.
Exploring SDG3: Good Health and Wellbeing
Collaborative evidence-based approaches to public policy and healthcare policy and practice are essential, not only in addressing inequalities but also in building trusted sustainable ways forward in which to ensure good health and wellbeing for all. The Journal of Headache and Pain supports submissions that address the SDG3 targets and indicators.
Read MoreAims and scope
Hallmarks of Primary Headache
The Journal of Headache and Pain announces a series of review articles on the Hallmarks of Primary Headaches.
Read the reviews:
Articles
-
-
GBD 2023: over twice the health loss from headache disorders among females compared with males, and one fifth of the loss is attributable to medication overuse
-
Bridging the gap between evidence and clinical practice for migraine headaches: a systematic review (2019–2024)
-
Sex-related disparities in migraine recognition and management: insights from a tertiary headache center cohort
-
Circulating CGRP as a diagnostic biomarker in female migraine patients: a single-center case-control study
Top cited articles 2022-2023
Review article | 12 April 2022
The global prevalence of headache: an update, with analysis of the influences of methodological factors on prevalence estimates
Lars Jacob Stovner, Knut Hagen, Mattias Linde & Timothy J. Steiner
Consensus article | 11 June 2022
European Headache Federation guideline on the use of monoclonal antibodies targeting the calcitonin gene related peptide pathway for migraine prevention-2022 update
Simona Sacco, Faisal Mohammad Amin, Messoud Ashina, Lars Bendtsen, Christina I. Deligianni, Raquel Gil-Gouveia, Zaza Katsarava, Antoinette MaassenVanDenBrink, Paolo Martelletti, Dimos-Dimitrios Mitsikostas, Raffaele Ornello, Uwe Reuter, Margarita Sanchez-del-Rio, Alexandra J. Sinclair, Gisela Terwindt, Derya Uluduz, Jan Versijpt & Christian Lampl
Review article | 1 August 2022
Long COVID headache
Claudio Tana, Enrico Bentivegna, Soo-Jin Cho, Andrea M. Harriott, David García-Azorín, Alejandro Labastida-Ramirez, Raffaele Ornello, Bianca Raffaelli, Eloísa Rubio Beltrán, Ruth Ruscheweyh & Paolo Martelletti
Research article | 3 January 2022
IL-17 crosses the blood-brain barrier to trigger neuroinflammation: a novel mechanism in nitroglycerin-induced chronic migraine
Hao Chen, Xueqian Tang, Jin Li, Bangyan Hu, Wenqin Yang, Meng Zhan, Tengyun Ma & Shijun Xu
Review article | 11 August 2022
Applying a biopsychosocial model to migraine: rationale and clinical implications
Chiara Rosignoli, Raffaele Ornello, Agnese Onofri, Valeria Caponnetto, Licia Grazzi, Alberto Raggi, Matilde Leonardi & Simona Sacco
Review article | 4 February 2023
Primary headache epidemiology in children and adolescents: a systematic review and meta-analysis
Agnese Onofri, Umberto Pensato, Chiara Rosignoli, William Wells-Gatnik, Emily Stanyer, Raffaele Ornello, Hui Zhou Chen, Federico De Santis, Angelo Torrente, Petr Mikulenka, Gabriele Monte, Karol Marschollek, Marta Waliszewska-Prosół, Wietse Wiels, Deirdre M. Boucherie, Dilara Onan, Fatemeh Farham, Linda Al-Hassany, Simona Sacco on behalf of the European Headache Federation School of Advanced Studies (EHF-SAS)
Research article | 9 April 2022
Fremanezumab in the prevention of high-frequency episodic and chronic migraine: a 12-week, multicenter, real-life, cohort study (the FRIEND study)
Piero Barbanti, Gabriella Egeo, Cinzia Aurilia, Florindo d’Onofrio, Maria Albanese, Ilaria Cetta, Paola Di Fiore, Maurizio Zucco, Massimo Filippi, Francesco Bono, Claudia Altamura, Stefania Proietti, Stefano Bonassi & Fabrizio Vernieri for the FRIEND-Study Group
Research article | 1 November 2022
Predictors of response to anti-CGRP monoclonal antibodies: a 24-week, multicenter, prospective study on 864 migraine patients
Piero Barbanti, Gabriella Egeo, Cinzia Aurilia, Claudia Altamura, Florindo d’Onofrio, Cinzia Finocchi, Maria Albanese, Marco Aguggia, Renata Rao, Maurizio Zucco, Fabio Frediani, Massimo Filippi, Roberta Messina, Sabina Cevoli, Antonio Carnevale, Giulia Fiorentini, Stefano Messina, Francesco Bono, Paola Torelli, Stefania Proietti, Stefano Bonassi & Fabrizio Vernieri for the Italian Migraine Registry study group
Review article | 20 February 2023
Genetics of migraine: where are we now?
Lou Grangeon, Kristin Sophie Lange, Marta Waliszewska-Prosół, Dilara Onan, Karol Marschollek, Wietse Wiels, Petr Mikulenka, Fatemeh Farham, Cédric Gollion & Anne Ducros on behalf of the European Headache Federation School of Advanced Studies (EHF-SAS)
Review article | 31 March 2022
Headache onset after vaccination against SARS-CoV-2: a systematic literature review and meta-analysis
Matteo Castaldo, Marta Waliszewska-Prosół, Maria Koutsokera, Micaela Robotti, Marcin Straburzyński, Loukia Apostolakopoulou, Mariarita Capizzi, Oneda Çibuku, Fidel Dominique Festin Ambat, Ilaria Frattale, Zukhra Gadzhieva, Erica Gallo, Anna Gryglas-Dworak, Gleni Halili, Asel Jusupova, Yana Koperskaya, Alo-Rainer Leheste, Maria Laura Manzo, Andrea Marcinnò, Antonio Marino, Petr Mikulenka, Bee Eng Ong, Burcu Polat, Zvonimir Popovic, Eduardo Rivera-Mancilla, Adina Maria Roceanu, Eleonora Rollo, Marina Romozzi, Claudia Ruscitto, Fabrizio Scotto di Clemente, Sebastian Strauss, Valentina Taranta, Maria Terhart, Iryna Tychenko, Simone Vigneri, Blazej Misiak, Paolo Martelletti & Alberto Raggi on behalf of the European Headache Federation School of Advanced Studies (EHF-SAS)
Publication years: 2022-2023
Source: Web of Science, data collected: January 2025
Trending articles
Click here to view which articles were talked about the most last month!
Graphical Abstracts
The Journal of Headache and Pain encourages authors to submit a graphical abstract as a supplementary file along with their manuscripts.
As an author submitting at The Journal of Headache and Pain you are entitled to a 20% discount on professionally produced graphical abstracts. Click here to find out more about the service, and your discount will be automatically applied when using this link.
Read MoreEuropean Headache Federation School of Advanced Studies
The European HeadacheFederation School of Advanced Studies (EHF-SAS) aims to support headache science and offers young EU scientists high quality educational activities to enhance their critical spirit and skills to face headache medicine from a multidisciplinary perspective.
The EHF-SAS covers the richness and diversity of headache medicine fields, including basic science, clinical science, and diagnostic science, and places an emphasis on collaborative projects. The European Headache Federation will support its fellows’ activities allowing them to independently build their own plan sided by the EHF-SAS Scientific Committee.
Official journal of
-
-
-
The Journal of Headache and Pain is the official journal of the European Headache Federation, Lifting The Burden, and the Asian Regional Consortium for Headache.
Follow
Annual Journal Metrics
-
Citation Impact
Journal Impact Factor: 7.9 (2024)
5-year Journal Impact Factor: 7.4 (2024)
Source Normalized Impact per Paper (SNIP): 2.066 (2024)SCImago Journal Rank (SJR): 2.066 (2024)Speed
Submission to first editorial decision (median days): 1
Submission to acceptance (median days): 45Usage 2024
Downloads: 2,713,192
Altmetric mentions: 1,825
- ISSN: 1129-2377 (electronic)
- ISSN: 1129-2369 (print)
Related reading
- Neuroimaging of Headache Disorders
- Clinical Scales for Headache Disorders
- Headache Disorders in Pandemic Conditions
- Non-Migraine Primary Headaches in Medicine
- Migraine in Medicine
- Novel Synthetic Drugs in Migraine
- Monoclonal Antibodies in Headache
- Neurophysiology of the Migraine Brain
- Societal Impact of Headache
- Neuromodulation in Headache and Facial Pain Management
- Cluster Headache and other Trigeminal Autonomic Cephalgias
- Peripheral Interventional Management in Headache
- Placebos and Nocebos in Headaches
- Gender and Migraine
- Headache and Comorbidities in Childhood and Adolescence
- Comorbidities in Headache Disorders
- Pharmacological Management of Headaches
- Pathophysiology of Headaches