Welcome to the web site of the Institute of Molecular Biology and Biotechnology of the Foundation for Research and Technology Hellas (IMBB-FORTH). IMBB is one of the most prominent life science research institutions in Greece, with an outstanding record of scientific achievements, state of the art infrastructure and a broad range of research, innovation and educational activities. IMBB’s main mission is to pursue cutting-edge research and promote scientific excellence.
How does the brain weave together subsequent memories? In a new Nature Neuroscience study, UCLA, Ohio State and IMBB researchers found that linked memories activate shared dendrites, causing synapse clustering as a result of local plasticity. The study reveals how dendrites enable memory linking,...
Artificial neural networks with dendrites: a possible solution for modern, energy-hungry, AI systems
IMBB researchers introduce a new type of artificial neural networks that incorporate characteristics of biological dendrites and can discriminate images accurately and robustly while using much fewer parameters. This new architecture paves the way for more compact and energy-efficient AI systems....
Activity-dependent K+ hotspots selectively boost the dendritic excitability of neurons, acting as 'volume knobs'
An international collaboration between scientists from IMBB, University of Copenhagen in Denmark and University of Bordeaux in France brings forward the novel concept that activity-dependent changes in the extracellular potassium concentration create local dendritic hotspots that transiently and ...
Distinct trafficking routes of polarized and non-polarized membrane cargoes in Aspergillus nidulans
In a study published in eLIFE Diallinas team established a genetic system to show the existence of distinct parallel trafficking routes for polarized and non-polarized membrane proteins, initiating early upon exit from the ER and bypassing the Golgi. This work provides a paradigm shift in membran...
IMBB researchers uncover the crucial role of a novel proteolytic pathway with metacaspases in maintaining protein homeostasis and lipid droplet function in seeds, processes which are vital for their longevity. Understanding these molecular mech...
Spermidine is vital for inducing autophagy and extending longevity during intermittent fasting
An international scientific collaboration between IMBB researchers, scientists from Paris Cité University in France, and the University of Graz in Austria reveals the conserved role of spermidine in regulating autophagy and extending lifespan during intermittent fasting.
Endonucleosis mediates internalization of cytoplasm into the nucleus
IMBB Researchers identified novel cellular survival mechanisms involving hyperploidization and endonucleosis, a membrane assisted internalization of cytoplasm into the nucleus. These cellular actions control genome instability caused by defective epigenetic regulation....
Reproductive status regulates the mitochondrial stress response
International collaboration between researchers at IMBB and University of Cologne reveals that germline reproductive signals impact the ability of somatic tissues to induce the mitochondrial unfolded protein response, highlighting the decline in reproductive capacity as a primary cause of proteos...
For the love of frontier research, or why Elon’s rockets keep blowing up
In a commissioned opinion article published in EMBO Reports, Professor and former president of FORTH Nektarios Tavernarakis cautions against the perils inherent in failing to prioritize funding and support of...
ΙΜΒΒ participated in the Researcher’s Night 2025 at FORTH
The Researcher’s Night 2025 at FORTH was held with great success!Young and old had the opportunity to get acquainted with the research conducted in the Institutes of FORTH. IMBB participated...
ΙΜΒΒ participates in "Researcher's Night 2025" organized by FORTH
"Researcher's Night 2025" will take place again this year at FORTH on Friday, September 26, 2025 (17:00-23:00). IMBB is actively participating with 14 groups....
CONTACT POINT: “And They Lived Happily Ever After: Ageing and Well-being”
The activities of “Contact Point” at FORTH is an original series of public discussions, each featuring a FORTH scientist and a distinguished artist. “Contact Point” brings Science and Culture into...
"Updates in Immunoglobulin gene looping and positionning"
Sandrine Le Noir, PhD
Permanent researcher CNRS Laboratoire CRIBL UMR CNRS7276 - Inserm1262 Université de Limoges
Oct 22, 2025 @ 12:45 - 13:30
Main amphitheater "G. Lianis ", FORTH’s bldg
Host: Babis Spilianakis
IMBB Colloquium
"The Promyelocytic Leukemia Protein (PML) Regulates Neural Stem Cell Physiology and confers Neuroprotection in a mouse model of Alzheimer’s Disease Pathology"
Sirago SPANOU
PhD candidate, Kretsovali Lab
Oct 17, 2025 @ 13:00 - 14:00
Seminar Room 1 "Costas Fotakis”, FORTH’s bldg
Joint Seminar Series in Translational and Clinical Medicine UoC Medical School - IMBB-FORTH – UCRC
"Empowering Omics Research: Integrating scRNA-Seq, Proteomics, and Protein-Protein Interaction Analysis. scRNA-Explorer Tutorial and an Introduction to UniReD and ProteoSign"
Dr Ismini Baltsavia
Postdoctoral Fellow, Computational Biology, Genomics and Bioinformatics Group, School of Medicine, UoC Prof. Ioannis Iliopoulos (Molecular Biology and Bioinformatics, School of Medicine, UoC) will provide a short introduction to the topic and speaker
Joint Seminar Series in Translational and Clinical Medicine UoC Medical School - IMBB-FORTH – UCRC
"Innovative technologies for implantable medical devices"
Prof. Nicola Baldini
Direttore Dipartimento Rizzoli-RIT (Research, Innovation & Technology) Direttore SC Scienze e Tecnologie Biomediche e Nanobiotecnologie IRCCS Istituto Ortopedico Rizzoli Dipartimento di Scienze Biomediche e Neuromotorie Alma Mater Studiorum - Università di Bologna
Oct 08, 2025 @ 15:00 - 16:00
Postgraduate Auditorium Medical School of the University of Crete
