Differentiation of optic disc edema and pseudopapilledema with deep learning on near-infrared reflectance images

BMC Ophthalmology

Table 5 Comparative performance of our model and three prior neuro-ophthalmic AI studies

See More Study (year)	Imaging modality	Clinical task/classes†	Test images (n)	Accuracy (%)	AUC	Sensitivity (%)	Specificity (%)
Our model	Near Infrared reflectance	ODE, PPE, normal	126	98.4	0.995 (ODE); 0.983 (PPE) 0.973 (N)	100 (ODE); 98 (PPE); 96 (N)	99 (ODE); 97 (PPE); 100 (N)
Milea et al., 2020 [21]	Dilated color fundus photographs	Papilledema vs. normal + other	1505	—	0.96	96.4	84.7
Ahn et al., 2019 [33]	Fundus photographs	Optic-neuropathy, PPE, normal	219	98.6 (ResNet)	0.999 (ResNet)	NR	NR
Lin et al., 2024 [35]	Mydriatic color fundus photographs	Papilledema vs. normal + other (pediatric)	898	89.6	0.99	98.0	94.1

ODE Optic Disc Edema, PPE Pseudopapilledema, N Normal, NR Not Reported, AUC Area Under the Curve
†Class labels shown as reported; “normal+other” indicates the one-vs-rest evaluation used by the authors

ISSN: 1471-2415